The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases
This guidance provides a data‐supported approach to the diagnostic, therapeutic, and
preventive aspects of nonalcoholic fatty liver disease (NAFLD) care. A “Guidance” document …
preventive aspects of nonalcoholic fatty liver disease (NAFLD) care. A “Guidance” document …
Challenges and opportunities in NASH drug development
SA Harrison, AM Allen, J Dubourg, M Noureddin… - Nature medicine, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and its more severe form, nonalcoholic
steatohepatitis (NASH), represent a growing worldwide epidemic and a high unmet medical …
steatohepatitis (NASH), represent a growing worldwide epidemic and a high unmet medical …
The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver
disease and affects nearly a quarter of the global population. The objective of this work was …
disease and affects nearly a quarter of the global population. The objective of this work was …
Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders
J Aron-Wisnewsky, C Vigliotti, J Witjes, P Le… - Nature Reviews …, 2020 - nature.com
Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …
Accuracy of FibroScan controlled attenuation parameter and liver stiffness measurement in assessing steatosis and fibrosis in patients with nonalcoholic fatty liver …
Background & Aims We estimated the accuracy of FibroScan vibration-controlled transient
elastography controlled attenuation parameter (CAP) and liver stiffness measurement …
elastography controlled attenuation parameter (CAP) and liver stiffness measurement …
Fibrosis stage but not NASH predicts mortality and time to development of severe liver disease in biopsy-proven NAFLD
Background & Aims Non-alcoholic fatty liver disease (NAFLD) is very common in the general
population, but identifying patients with increased risk of mortality and liver-specific morbidity …
population, but identifying patients with increased risk of mortality and liver-specific morbidity …
[HTML][HTML] Non-alcoholic fatty liver disease: A patient guideline
This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty
liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and …
liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and …
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis
The mechanisms that drive nonalcoholic fatty liver disease (NAFLD) remain incompletely
understood. This large multicenter study characterized the transcriptional changes that occur …
understood. This large multicenter study characterized the transcriptional changes that occur …
Cellular senescence drives age-dependent hepatic steatosis
The incidence of non-alcoholic fatty liver disease (NAFLD) increases with age. Cellular
senescence refers to a state of irreversible cell-cycle arrest combined with the secretion of …
senescence refers to a state of irreversible cell-cycle arrest combined with the secretion of …
[HTML][HTML] Current guidelines for the management of non-alcoholic fatty liver disease: A systematic review with comparative analysis
S Leoni, F Tovoli, L Napoli, I Serio, S Ferri… - World journal of …, 2018 - ncbi.nlm.nih.gov
The current epidemic of non-alcoholic fatty liver disease (NAFLD) is resha** the field of
hepatology all around the world. The widespread diffusion of metabolic risk factors such as …
hepatology all around the world. The widespread diffusion of metabolic risk factors such as …