The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

Humans require a plethora of higher cognitive skills to perform executive functions, such as
reasoning, planning, language and social interactions, which are regulated predominantly …

An increasing amount of research effort is being directed toward investigating the neural
bases of social cognition from a systems neuroscience perspective. Evidence from multiple …

Prefrontal cortex (PFC) means different things to different people. In recent years, there has
been a major increase in publications on the PFC, especially using mice. However …

To compare findings across species, neuroscience relies on cross-species homologies,
particularly in terms of brain areas. For cingulate cortex, a structure implicated in behavioural …

The anterior cingulate cortex (ACC) is implicated in a broad range of behaviors and
cognitive processes, but it has been unclear what contribution, if any, the ACC makes to …

Apathy is a debilitating syndrome associated with many neurological disorders, including
several common neurodegenerative diseases such as Parkinson's disease and Alzheimer's …

The causal role of an area within a neural network can be determined by interfering with its
activity and measuring the impact. Many current reversible manipulation techniques have …

Dorsal anterior cingulate cortex (dACC) carries a wealth of value-related information
necessary for regulating behavioral flexibility and persistence. It signals error and reward …

Decisions take time, and as a rule more difficult decisions take more time. But this only
raises the question of what consumes the time. For decisions informed by a sequence of …