Protein 3d graph structure learning for robust structure-based protein property prediction

Y Huang, S Li, L Wu, J Su, H Lin, O Zhang… - Proceedings of the …, 2024 - ojs.aaai.org
Protein structure-based property prediction has emerged as a promising approach for
various biological tasks, such as protein function prediction and sub-cellular location …

Metaenzyme: Meta pan-enzyme learning for task-adaptive redesign

J Zheng, H Zhang, Q Xu, AP Zeng, SZ Li - Proceedings of the 32nd ACM …, 2024 - dl.acm.org
Enzyme design plays a crucial role in both industrial production and biology. However, this
field faces challenges due to the lack of comprehensive benchmarks and the complexity of …

Progressive multi-modality learning for inverse protein folding

J Zheng, SZ Li - … Conference on Multimedia and Expo (ICME), 2024 - ieeexplore.ieee.org
While deep generative models show promise for learning inverse protein folding directly
from data, the lack of publicly available structure-sequence pairings limits their …

Protein engineering in the deep learning era

B Zhou, Y Tan, Y Hu, L Zheng, B Zhong, L Hong - mLife, 2024 - Wiley Online Library
Advances in deep learning have significantly aided protein engineering in addressing
challenges in industrial production, healthcare, and environmental sustainability. This …

Pan-protein Design Learning Enables Task-adaptive Generalization for Low-resource Enzyme Design

J Zheng, G Wang, H Zhang, SZ Li - arxiv preprint arxiv:2411.17795, 2024 - arxiv.org
Computational protein design (CPD) offers transformative potential for bioengineering, but
current deep CPD models, focused on universal domains, struggle with function-specific …

Gentle-CLIP: Exploring Aligned Semantic In Low-Quality Multimodal Data With Soft Alignment

Z Song, Z Zang, Y Wang, G Yang, J Zheng… - arxiv preprint arxiv …, 2024 - arxiv.org
Multimodal fusion breaks through the barriers between diverse modalities and has already
yielded numerous impressive performances. However, in various specialized fields, it is …

Sable: Bridging the Gap in Protein Structure Understanding with an Empowering and Versatile Pre-training Paradigm

Q Ye, X Chen, H Huang, M Zeng, J Yu, X Gong - 2024 - researchsquare.com
Protein pre-training has emerged as a transformative approach for solving diverse biological
tasks. While many contemporary methods focus on sequence-based language models …