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Traumatic brain injury: current treatment strategies and future endeavors
Traumatic brain injury (TBI) presents in various forms ranging from mild alterations of
consciousness to an unrelenting comatose state and death. In the most severe form of TBI …
consciousness to an unrelenting comatose state and death. In the most severe form of TBI …
Cellular infiltration in traumatic brain injury
Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …
Animal models of traumatic brain injury and assessment of injury severity
Traumatic brain injury (TBI) contributes a major cause of death, disability, and mental health
disorders. Most TBI patients suffer long-term post-traumatic stress disorder, cognitive …
disorders. Most TBI patients suffer long-term post-traumatic stress disorder, cognitive …
Animal models of traumatic brain injury
Y **ong, A Mahmood, M Chopp - Nature Reviews Neuroscience, 2013 - nature.com
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity both in civilian life
and on the battlefield worldwide. Survivors of TBI frequently experience long-term disabling …
and on the battlefield worldwide. Survivors of TBI frequently experience long-term disabling …
Pathophysiology associated with traumatic brain injury: current treatments and potential novel therapeutics
ML Pearn, IR Niesman, J Egawa, A Sawada… - Cellular and molecular …, 2017 - Springer
Traumatic brain injury (TBI) is one of the leading causes of death of young people in the
developed world. In the United States alone, 1.7 million traumatic events occur annually …
developed world. In the United States alone, 1.7 million traumatic events occur annually …
Pathogenesis of brain edema and investigation into anti-edema drugs
S Michinaga, Y Koyama - International journal of molecular sciences, 2015 - mdpi.com
Brain edema is a potentially fatal pathological state that occurs after brain injuries such as
stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid …
stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid …
Revisiting excitotoxicity in traumatic brain injury: from bench to bedside
D Baracaldo-Santamaría, DF Ariza-Salamanca… - Pharmaceutics, 2022 - mdpi.com
Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality.
Consequences vary from mild cognitive impairment to death and, no matter the severity of …
Consequences vary from mild cognitive impairment to death and, no matter the severity of …
Repeated mild traumatic brain injury: potential mechanisms of damage
Mild traumatic brain injury (mTBI) represents a significant public healthcare concern,
accounting for the majority of all head injuries. While symptoms are generally transient …
accounting for the majority of all head injuries. While symptoms are generally transient …
Classification of traumatic brain injury for targeted therapies
KE Saatman, AC Duhaime, R Bullock… - Journal of …, 2008 - liebertpub.com
The heterogeneity of traumatic brain injury (TBI) is considered one of the most significant
barriers to finding effective therapeutic interventions. In October, 2007, the National Institute …
barriers to finding effective therapeutic interventions. In October, 2007, the National Institute …
An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanisms
Background Traumatic brain injury (TBI) is a major cause of morbidity and mortality, affecting
millions annually worldwide. Although the majority of TBI patients return to premorbid …
millions annually worldwide. Although the majority of TBI patients return to premorbid …