Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …

The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …

Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …

Butyrate, a main product of gut microbial fermentation, has been recognized as an important
mediator of gut microbiota regulation in whole body energy homeostasis. However, the …

Evidence is increasing that disturbances in the gut microbiome may play a significant role in
the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end …

Overweight and obesity have become a world-wide problem. However, effective intervention
approaches are limited. Brown adipose tissue, which helps maintain body temperature and …

The worldwide incidence of obesity and its sequelae, such as type 2 diabetes mellitus, have
reached pandemic levels. Central to the development of these metabolic disorders is …

Temperature is a prominent abiotic environmental variable that drives the adaptive
trajectories of animal lineages and structures the composition of animal communities. Global …