Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …
various cardiac diseases, which remain the most common cause of death in the developed …
A framework for designing patient‐specific bioprosthetic heart valves using immersogeometric fluid–structure interaction analysis
Numerous studies have suggested that medical image derived computational mechanics
models could be developed to reduce mortality and morbidity due to cardiovascular …
models could be developed to reduce mortality and morbidity due to cardiovascular …
A contact formulation based on a volumetric potential: Application to isogeometric simulations of atrioventricular valves
This work formulates frictionless contact between solid bodies in terms of a repulsive
potential energy term and illustrates how numerical integration of the resulting forces is …
potential energy term and illustrates how numerical integration of the resulting forces is …
A noninvasive method for the determination of in vivo mitral valve leaflet strains
Assessment of mitral valve (MV) function is important in many diagnostic, prognostic, and
surgical planning applications for treatment of MV disease. Yet, to date, there are no …
surgical planning applications for treatment of MV disease. Yet, to date, there are no …
A comprehensive pipeline for multi‐resolution modeling of the mitral valve: V alidation, computational efficiency, and predictive capability
Multiple studies have demonstrated that the pathological geometries unique to each patient
can affect the durability of mitral valve (MV) repairs. While computational modeling of the MV …
can affect the durability of mitral valve (MV) repairs. While computational modeling of the MV …
Development of a functionally equivalent model of the mitral valve chordae tendineae through topology optimization
Ischemic mitral regurgitation (IMR) is a currently prevalent disease in the US that is projected
to become increasingly common as the aging population grows. In recent years, image …
to become increasingly common as the aging population grows. In recent years, image …
In vivo assessment of mitral valve leaflet remodelling following myocardial infarction
Abstract Each year, more than 40,000 people undergo mitral valve (MV) repair surgery
domestically to treat regurgitation caused by myocardial infarction (MI). Although continual …
domestically to treat regurgitation caused by myocardial infarction (MI). Although continual …
Tissue loading and microstructure regulate the deformation of embedded nerve fibres: predictions from single-scale and multiscale simulations
V Zarei, S Zhang, BA Winkelstein… - Journal of the Royal …, 2017 - royalsocietypublishing.org
Excessive deformation of nerve fibres (axons) in the spinal facet capsular ligaments (FCLs)
can be a cause of pain. The axons are embedded in the fibrous extracellular matrix (ECM) of …
can be a cause of pain. The axons are embedded in the fibrous extracellular matrix (ECM) of …
An object-based shale permeability model: non-Darcy gas flow, sorption, and surface diffusion effects
Shale samples consist of two major components: organic matter (OM) and inorganic mineral
component (iOM). Each component has its distinct pore network topology and morphology …
component (iOM). Each component has its distinct pore network topology and morphology …
Multi-resolution geometric modeling of the mitral heart valve leaflets
An essential element of cardiac function, the mitral valve (MV) ensures proper directional
blood flow between the left heart chambers. Over the past two decades, computational …
blood flow between the left heart chambers. Over the past two decades, computational …