BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

BACKGROUND Male infertility affects> 20 million men worldwide and represents a major
health concern. Although multifactorial, male infertility has a strong genetic basis which has …

For over 30 years, sperm morphology assessment has been one of the most common tests
in evaluation of fertility. This review examines the clinical relevance of sperm morphology …

Objective To evaluate whether male fertility status and/or embryo quality during in vitro
fertilization (IVF) therapy can be predicted based on genomewide sperm deoxyribonucleic …

Despite the high prevalence of male infertility, very little is known about its etiology. In recent
years however, advances in gene sequencing technology have enabled us to identify a …

Infertility, defined by the inability of conceiving a child after 1 year is estimated to concern
approximately 50 million couples worldwide. As the male gamete is readily accessible and …

Infertility is a relatively common health condition, affecting nearly 7% of all couples.
Clinically, it is a highly heterogeneous pathology with a complex etiology that includes …

Chromosomal abnormalities, including microdeletions and microduplications, have long
been associated with abnormal developmental outcomes. Early discoveries relied on a …

Spermatozoa are polarized cells with a head and a flagellum joined by the connecting
piece. Head integrity is critical for normal sperm function, and head defects consistently lead …

Teratozoospermia is characterized by the presence of spermatozoa with abnormal
morphology over 85% in sperm. When all the spermatozoa display a unique abnormality …