Deep learning in the biomedical applications: Recent and future status

R Zemouri, N Zerhouni, D Racoceanu - Applied Sciences, 2019 - mdpi.com
Deep neural networks represent, nowadays, the most effective machine learning technology
in biomedical domain. In this domain, the different areas of interest concern the Omics (study …

Engineered nanomaterials: The challenges and opportunities for nanomedicines

F Albalawi, MZ Hussein, S Fakurazi… - International journal of …, 2021 - Taylor & Francis
The emergence of nanotechnology as a key enabling technology over the past years has
opened avenues for new and innovative applications in nanomedicine. From the business …

Learning functional properties of proteins with language models

S Unsal, H Atas, M Albayrak, K Turhan… - Nature Machine …, 2022 - nature.com
Data-centric approaches have been used to develop predictive methods for elucidating
uncharacterized properties of proteins; however, studies indicate that these methods should …

How to approach machine learning-based prediction of drug/compound–target interactions

H Atas Guvenilir, T Doğan - Journal of Cheminformatics, 2023 - Springer
The identification of drug/compound–target interactions (DTIs) constitutes the basis of drug
discovery, for which computational predictive approaches have been developed. As a …

Identifying antimicrobial peptides using word embedding with deep recurrent neural networks

MN Hamid, I Friedberg - Bioinformatics, 2019 - academic.oup.com
Motivation Antibiotic resistance constitutes a major public health crisis, and finding new
sources of antimicrobial drugs is crucial to solving it. Bacteriocins, which are bacterially …

Immune2vec: Embedding B/T Cell Receptor Sequences in ℝ N Using Natural Language Processing

M Ostrovsky-Berman, B Frankel, P Polak… - Frontiers in …, 2021 - frontiersin.org
The adaptive branch of the immune system learns pathogenic patterns and remembers them
for future encounters. It does so through dynamic and diverse repertoires of T-and B-cell …

Sequence pre-training-based graph neural network for predicting lncRNA-miRNA associations

Z Wang, S Liang, S Liu, Z Meng, J Wang… - Briefings in …, 2023 - academic.oup.com
MicroRNAs (miRNAs) silence genes by binding to messenger RNAs, whereas long non-
coding RNAs (lncRNAs) act as competitive endogenous RNAs (ceRNAs) that can relieve …

Protein feature engineering framework for AMPylation site prediction

H Prabhu, H Bhosale, A Sane, R Dhadwal… - Scientific Reports, 2024 - nature.com
AMPylation is a biologically significant yet understudied post-translational modification
where an adenosine monophosphate (AMP) group is added to Tyrosine and Threonine …

Using the Chou's 5-steps rule to predict splice junctions with interpretable bidirectional long short-term memory networks

A Dutta, A Dalmia, R Athul, KK Singh… - Computers in Biology and …, 2020 - Elsevier
Neural models have been able to obtain state-of-the-art performances on several genome
sequence-based prediction tasks. Such models take only nucleotide sequences as input …

Unsupervised representation learning of DNA sequences

V Agarwal, N Reddy, A Anand - arxiv preprint arxiv:1906.03087, 2019 - arxiv.org
Recently several deep learning models have been used for DNA sequence based
classification tasks. Often such tasks require long and variable length DNA sequences in the …