Multiscale computational modeling of vascular adaptation: a systems biology approach using agent-based models

A Corti, M Colombo, F Migliavacca… - … in Bioengineering and …, 2021 - frontiersin.org
The widespread incidence of cardiovascular diseases and associated mortality and
morbidity, along with the advent of powerful computational resources, have fostered an …

Engineering innovations in medicine and biology: Revolutionizing patient care through mechanical solutions

EG Hanna, K Younes, R Roufayel, M Khazaal… - Heliyon, 2024 - cell.com
The overlap between mechanical engineering and medicine is expanding more and more
over the years. Engineers are now using their expertise to design and create functional …

Computational hemodynamics in human vasculature: a review on role of rheology, multiphase flow, and fluid–structure interaction

SR Morab, A Sharma, JS Murallidharan - Journal of the Indian Institute of …, 2024 - Springer
Efficient and accurate computational model for blood flow dynamics (hemodynamics), is
essential for determining optimal treatment strategy, diagnosis, and pathology identification …

[BOOK][B] Vascular Biomechanics

TC Gasser - 2021 - Springer
The development of the vascular system was a critical step in the evolution of species. It
allowed organisms to meet the growing metabolic demands and opened the door for the …

Computational fluid dynamics as supporting technology for coronary artery disease diagnosis and treatment: an international survey

C Chiastra, M Zuin, G Rigatelli, F D'Ascenzo… - Frontiers in …, 2023 - frontiersin.org
Background Computational fluid dynamics (CFD) is emerging as an effective technology
able to improve procedural outcomes and enhance clinical decision-making in patients with …

A review of computational methodologies to predict the fractional flow reserve in coronary arteries with stenosis

M Fernandes, LC Sousa, CC António, S Silva… - Journal of …, 2024 - Elsevier
Computational methodologies for predicting the fractional flow reserve (FFR) in coronary
arteries with stenosis have gained significant attention due to their potential impact on …

The Role of Shear Stress in Coronary Artery Disease

G Siasos, V Tsigkou, AU Coskun… - Current Topics in …, 2023 - ingentaconnect.com
Coronary artery disease is the leading cause of morbidity and mortality worldwide,
especially in developed countries, with an increasing incidence in develo** countries …

Consistency in geometry among coronary atherosclerotic plaques extracted from computed tomography angiography

H Liu, A Wingert, X Wang, J Zhang, J Sun… - Frontiers in …, 2021 - frontiersin.org
Background: The three-dimensional (3D) geometry of coronary atherosclerotic plaques is
associated with plaque growth and the occurrence of coronary artery disease. However …

Mathematical modeling of plaque progression and associated microenvironment: How far from predicting the fate of atherosclerosis?

Y Cai, Z Li - Computer Methods and Programs in Biomedicine, 2021 - Elsevier
Mathematical modeling contributes to pathophysiological research of atherosclerosis by
hel** to elucidate mechanisms and by providing quantitative predictions that can be …

Integrating Computational and Biological Hemodynamic Approaches to Improve Modeling of Atherosclerotic Arteries

TNAM Vuong, M Bartolf‐Kopp, K Andelovic… - Advanced …, 2024 - Wiley Online Library
Atherosclerosis is the primary cause of cardiovascular disease, resulting in mortality,
elevated healthcare costs, diminished productivity, and reduced quality of life for individuals …