Epidemiological and interventional human studies, as well as experiments in animal
models, strongly indicate that helminth parasitic infections can confer protection from …

Innate immune system provides the first line of defense against pathogenic organisms. It has
a varied and large collection of molecules known as pattern recognition receptors (PRRs) …

Toll-like receptor 4 (TLR4), together with MD-2, binds bacterial endotoxins (E) with high
affinity, triggering formation of the activated homodimer (E. MD-2. TLR4) 2. Activated TLR4 …

Chronic pancreatitis is characterized by progressive loss of exocrine and endocrine
functions of the pancreas and is considered to be the single most important cause for …

Despite the tremendous progress in healthcare sectors, a number of life-threatening
infectious, inflammatory, and autoimmune diseases are continuously challenging mankind …

Thioredoxin is a low molecular weight redox-active protein of filarial parasite that plays a
crucial role in downregulating the host immune response to prolong the survival of the …

TLR4, the innate immunity receptor for bacterial endotoxins, plays a pivotal role in the
induction of inflammatory responses. There is a need to develop molecules that block either …

Toll-like receptors (TLRs) are type I transmembrane proteins that are key regulators of both
innate and adaptive immune responses. To protect the host from viral and bacterial threats …

Background Berberine is an isoquinoline alkaloid mainly extracted from Rhizoma Coptidis
and has been shown to possess a potent inhibitory activity against bacterial. However, the …

Background: Regular exercise, particularly moderate-intensity continuous training (MICT),
can improve immune function. Natural killer (NK) cells, a subset of lymphocytes that react to …