Alzheimer's disease (AD) is an age-related devastating neurodegenerative disorder, which
severely impacts on the global economic development and healthcare system. Though AD …

Platelets play a variety of roles in vascular biology and are best recognized as primary
hemostasis and thrombosis mediators. Platelets have a large number of receptors and …

Low-grade, chronic inflammation has been associated with many diseases of aging, but the
mechanisms responsible for producing this inflammation remain unclear. Inflammasomes …

Human aging is characterized by both physical and physiological frailty that profoundly
affects the immune system. In this context aging is associated with declines in adaptive and …

From a biological point of view, aging can be considered a progressive inability of an
organism to react to stress, maintain homeostasis, and survive unfavourable changes during …

Exosomes are small bilipid layer-enclosed extracellular vesicles that can be found in tissues
and biological fluids. As a key cell-to-cell and distant communication mediator, exosomes …

Inflammation is one of the body's first lines of defense in response to injury or infection, and
increased inflammation is found in many diseases. Acute inflammation is a nonspecific …

Alzheimer's disease (AD) is a neurodegenerative condition characterized by the formation of
amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia …

The possibility that Alzheimer's disease (AD) has a microbial aetiology has been proposed
by several researchers. Here, we provide evidence that tissue from the central nervous …

Alzheimer's disease (AD) is the leading cause of dementia in elderly people. The etiology of
this disease remains a matter of intensive research in many laboratories. We have advanced …