Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma

P Johnson, Q Zhou, DY Dao, YMD Lo - … reviews Gastroenterology & …, 2022 - nature.com
Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal causes of cancer-
related death worldwide. The treatment of HCC remains challenging and is largely …

The future of early cancer detection

RC Fitzgerald, AC Antoniou, L Fruk, N Rosenfeld - Nature medicine, 2022 - nature.com
A proactive approach to detecting cancer at an early stage can make treatments more
effective, with fewer side effects and improved long-term survival. However, as detection …

Nasopharyngeal carcinoma: an evolving paradigm

KCW Wong, EP Hui, KW Lo, WKJ Lam… - Nature reviews Clinical …, 2021 - nature.com
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …

Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies

YMD Lo, DSC Han, P Jiang, RWK Chiu - Science, 2021 - science.org
BACKGROUND Liquid biopsies that are based on analysis of cell-free DNA from plasma
offer diagnostic information that is otherwise accessible conventionally through invasive …

[HTML][HTML] Investigation of long COVID prevalence and its relationship to Epstein-Barr virus reactivation

JE Gold, RA Okyay, WE Licht, DJ Hurley - Pathogens, 2021 - mdpi.com
Pathogens | Free Full-Text | Investigation of Long COVID Prevalence and Its Relationship to
Epstein-Barr Virus Reactivation Next Article in Journal Epidemiological Aspects of Maternal …

The Chinese Society of Clinical Oncology (CSCO) clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma

LL Tang, YP Chen, CB Chen, MY Chen… - Cancer …, 2021 - Wiley Online Library
Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor originating in the
nasopharynx and has a high incidence in Southeast Asia and North Africa. To develop these …

Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics

P Song, LR Wu, YH Yan, JX Zhang, T Chu… - Nature biomedical …, 2022 - nature.com
Cell-free DNA (cfDNA) in the circulating blood plasma of patients with cancer contains
tumour-derived DNA sequences that can serve as biomarkers for guiding therapy, for the …

[HTML][HTML] Anti–Epstein–Barr virus BNLF2b for mass screening for nasopharyngeal cancer

T Li, F Li, X Guo, C Hong, X Yu, B Wu… - … England Journal of …, 2023 - Mass Medical Soc
Background Population screening of asymptomatic persons with Epstein–Barr virus (EBV)
DNA or antibodies has improved the diagnosis of nasopharyngeal carcinoma and survival …

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond

L Keller, Y Belloum, H Wikman, K Pantel - British journal of cancer, 2021 - nature.com
Cell-free DNA (cfDNA) derived from tumours is present in the plasma of cancer patients. The
majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal …