Advancement in solubilization approaches: A step towards bioavailability enhancement of poorly soluble drugs

L Kumari, Y Choudhari, P Patel, GD Gupta, D Singh… - Life, 2023 - mdpi.com
A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …

Advances in smart mesoporous carbon nanoplatforms for photothermal–enhanced synergistic cancer therapy

S Feng, J Lu, K Wang, D Di, Z Shi, Q Zhao… - Chemical Engineering …, 2022 - Elsevier
Mesoporous carbon nanoparticles (MCNs) and their derivatives have been extensively
explored in photothermal therapy (PTT) based cancer treatment, due to their unique …

Astaxanthin activated the Nrf2/HO-1 pathway to enhance autophagy and inhibit ferroptosis, ameliorating acetaminophen-induced liver injury

X Cai, S Hua, J Deng, Z Du, D Zhang… - … applied materials & …, 2022 - ACS Publications
Acetaminophen (APAP)-induced liver injury (AILI) is a common liver disease in clinical
practice. Only one clinically approved drug, N-acetylcysteine (NAC), for the treatment of AILI …

Mesoporous silica nanoparticles: A comprehensive review on synthesis and recent advances

R Narayan, UY Nayak, AM Raichur, S Garg - Pharmaceutics, 2018 - mdpi.com
Recent advancements in drug delivery technologies utilizing a variety of carriers have
resulted in a path-breaking revolution in the approach towards diagnosis and therapy alike …

Multifaceted application of silica nanoparticles. A review

PG Jeelani, P Mulay, R Venkat, C Ramalingam - Silicon, 2020 - Springer
Nanoparticles have immense industrial, biotechnological, and biomedical/pharmaceutical
applications due to their pliability in structure, size, biocompatibility, high surface area, and …

[HTML][HTML] Mesoporous silica nanoparticles for therapeutic/diagnostic applications

S Jafari, H Derakhshankhah, L Alaei, A Fattahi… - Biomedicine & …, 2019 - Elsevier
Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as
high surface area, large pore size, good biocompatibility and biodegradability, stable …

[HTML][HTML] Mesoporous silica nanoparticles for drug and gene delivery

Y Zhou, G Quan, Q Wu, X Zhang, B Niu, B Wu… - … pharmaceutica sinica B, 2018 - Elsevier
Mesoporous silica nanoparticles (MSNs) are attracting increasing interest for potential
biomedical applications. With tailored mesoporous structure, huge surface area and pore …

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

[HTML][HTML] Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

BJ Boyd, CAS Bergström, Z Vinarov, M Kuentz… - European Journal of …, 2019 - Elsevier
Poorly water-soluble drugs continue to be a problematic, yet important class of
pharmaceutical compounds for treatment of a wide range of diseases. Their prevalence in …

[HTML][HTML] A review of the antibacterial, fungicidal and antiviral properties of selenium nanoparticles

DA Serov, VV Khabatova, V Vodeneev, R Li… - Materials, 2023 - mdpi.com
The resistance of microorganisms to antimicrobial drugs is an important problem worldwide.
To solve this problem, active searches for antimicrobial components, approaches and …