Type 2 diabetes mellitus (T2DM) is a global pandemic, as evident from the global
cartographic picture of diabetes by the International Diabetes Federation (http://www …

Despite treatment with statins, patients with elevated low-density lipoprotein cholesterol
(LDL-C) and triglycerides remain at increased risk for adverse cardiovascular events …

Methods A total of 8,749 non-diabetic participants, aged 45–73 years, were followed up for
5.9 years. New diabetes was diagnosed in 625 men by means of an OGTT, HbA 1c≥ …

Statins, among the most commonly prescribed drugs worldwide, are cholesterol-lowering
agents used to manage and prevent cardiovascular and coronary heart diseases. Recently …

Background: Metabolic activity is the basic life activity of organisms and the fundamental for
maintaining body functions. With the improvement of living standards, the incidence of …

Importance Statin therapy has been associated with increased insulin resistance; however,
its clinical implications for diabetes control among patients with diabetes is unknown …

Background Statins are a class of therapeutics used to regulate serum cholesterol and
reduce the risk of heart disease. Although statins are highly effective in removing cholesterol …

Objective—8-Hydroxy-2, 2, 14, 14-tetramethylpentadecanedioic acid (ETC-1002) is a small
molecule with a unique mechanism of action shown in nonclinical studies to modulate …

The debate whether statins, 3-hydroxymethyl-3-methylglutaryl coenzyme A reductase
inhibitors, are safe to use has been raging since their introduction in 1987. Statins are …

The aggregate of large clinical trials supports the notion that statins modestly increase the
risk of incident diabetes. Because diabetes is a risk equivalent condition for coronary and …