Background The long non-coding RNA (lncRNA), MALAT1, plays a key role in the
development of different cancers, and its expression is associated with worse prognosis in …

Background Mismatch repair (MMR)/microsatellite instability (MSI) and tumor mutational
burden (TMB) are independent biomarkers that complement each other for predicting …

Background Uveal melanoma (UVM) is the leading cause of eye-related mortality
worldwide. This study aimed to explore the expression and prognostic value of matrix …

Background Growing evidence has demonstrated immune reactivity as a confirmed
important carcinogenesis and therapy efficacy for clear cell renal cell carcinoma (ccRCC) …

Background Metabolic reprogramming is one of the hallmarks of cancer cells. The pentose
phosphate pathway (PPP), a branch of glycolysis, is an important metabolic pathway for the …

Background The mutational profile of cancer reflects the activity of the mutagenic processes
which have been operative throughout the lineage of the cancer cell. These processes leave …

Background Hepatocellular carcinoma (HCC) is one of the most common cancers. The
discovery of specific genes severing as biomarkers is of paramount significance for cancer …

Background Identification of master regulators (MRs) using transcriptome data in cervical
cancer (CC) could help us to develop biomarkers and find novel drug targets to fight this …

Abstract Background Circulating tumor cells (CTCs) has been demonstrated as a promising
liquid biopsy marker for breast cancer (BC). However, the intra-patient heterogeneity of …

Background The pathogenesis and developmental mechanism of early-stage (FIGO 2009
IA2-IIA2) cervical cancer (CC) remain unclear. Seeking novel molecular biomarkers based …