Prevalence, incidence, and trends of epilepsy among children and adolescents in Africa: a systematic review and meta-analysis

G Biset, N Abebaw, NA Gebeyehu, N Estifanos… - BMC Public Health, 2024 - Springer
Background Epilepsy contributes to a significant disease burden in children and
adolescents worldwide. The incidence of childhood epilepsy is threefold higher in low and …

Onchocerciasis-associated epilepsy: an update and future perspectives

A Hadermann, LJ Amaral, G Van Cutsem… - Trends in …, 2023 - cell.com
Onchocerciasis-associated epilepsy (OAE) is an important neglected public health problem
in areas with high ongoing onchocerciasis transmission. The risk that children in such areas …

Onchocerca volvulus and epilepsy: A comprehensive review using the Bradford Hill criteria for causation

R Colebunders, AK Njamnshi, S Menon… - PLoS neglected …, 2021 - journals.plos.org
Background The possibility that onchocerciasis may cause epilepsy has been suggested for
a long time, but thus far, an etiological link has not been universally accepted. The objective …

Effect of onchocerciasis elimination measures on the incidence of epilepsy in Maridi, South Sudan: a 3-year longitudinal, prospective, population-based study

SR Jada, LJ Amaral, T Lakwo, JY Carter… - The Lancet Global …, 2023 - thelancet.com
Background High onchocerciasis transmission predisposes endemic communities to a high
epilepsy burden. The 4· 4% epilepsy prevalence documented in 2018 in Maridi, South …

[HTML][HTML] Case definitions for onchocerciasis-associated epilepsy and nodding syndrome: A focused review

G Van Cutsem, JNS Fodjo, MCJ Dekker… - … : European Journal of …, 2023 - Elsevier
Onchocerciasis-associated epilepsy (OAE) is an important but neglected public health
problem in onchocerciasis-endemic areas with insufficient or inadequate onchocerciasis …

Impact of a bi-annual community-directed treatment with ivermectin programme on the incidence of epilepsy in an onchocerciasis-endemic area of Mahenge …

D Bhwana, LJ Amaral, A Mhina… - PLoS neglected …, 2023 - journals.plos.org
Background Community-directed treatment with ivermectin (CDTi) is used to eliminate
onchocerciasis. However, despite 25 years of annual CDTi in Mahenge, Tanzania, the …

Impact of annual community-directed treatment with ivermectin on the incidence of epilepsy in Mvolo, a two-year prospective study

LJ Amaral, SR Jada, AK Ndjanfa… - PLoS neglected …, 2024 - journals.plos.org
Objectives The potential impact of cumulative community-directed treatment with ivermectin
(CDTI) on epilepsy epidemiology in Mvolo County, South Sudan, an onchocerciasis …

The role of the Maridi Dam in causing an onchocerciasis-associated epilepsy epidemic in Maridi, South Sudan: an epidemiological, sociological, and entomological …

TL Lakwo, S Raimon, M Tionga, JN Siewe Fodjo… - Pathogens, 2020 - mdpi.com
Background: An epilepsy prevalence of 4.4% was documented in onchocerciasis-endemic
villages close to the Maridi River in South Sudan. We investigated the role of the Maridi dam …

Changes in epilepsy burden after onchocerciasis elimination in a hyperendemic focus of western Uganda: a comparison of two population-based, cross-sectional …

N Gumisiriza, C Kaiser, G Asaba, H Onen… - The Lancet Infectious …, 2020 - thelancet.com
Background In 1994, prevalence and incidence of epilepsy were high in the Itwara
onchocerciasis focus (western Uganda), and cases of nodding and Nakalanga syndrome …

Prevalence and incidence of nodding syndrome and other forms of epilepsy in onchocerciasis-endemic areas in northern Uganda after the implementation of …

N Gumisiriza, F Mubiru, JN Siewe Fodjo… - Infectious Diseases of …, 2020 - Springer
Background Around 2007, a nodding syndrome (NS) epidemic appeared in onchocerciasis-
endemic districts of northern Uganda, where ivermectin mass distribution had never been …