Traumatic spinal cord injury—repair and regeneration

CS Ahuja, S Nori, L Tetreault, J Wilson, B Kwon… - …, 2017 - journals.lww.com
BACKGROUND: Traumatic spinal cord injuries (SCI) have devastating consequences for the
physical, financial, and psychosocial well-being of patients and their caregivers. Expediently …

Assessment and management of acute spinal cord injury: From point of injury to rehabilitation

LD Hachem, CS Ahuja, MG Fehlings - The journal of spinal cord …, 2017 - Taylor & Francis
Context: Spinal cord injury (SCI) is a devastating condition that can lead to significant
neurological impairment and reduced quality of life. Despite advancements in our …

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data

JH Badhiwala, JR Wilson, CD Witiw, JS Harrop… - The Lancet …, 2021 - thelancet.com
Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …

Management of acute traumatic spinal cord injury: a review of the literature

TY Wang, C Park, H Zhang, S Rahimpour… - Frontiers in …, 2021 - frontiersin.org
Traumatic spinal cord injury (TSCI) is a debilitating disease that poses significant functional
and economic burden on both the individual and societal levels. Prognosis is dependent on …

A clinical practice guideline for the management of patients with acute spinal cord injury and central cord syndrome: recommendations on the timing (≤ 24 hours …

MG Fehlings, LA Tetreault, JR Wilson… - Global spine …, 2017 - journals.sagepub.com
Objective: To develop recommendations on the timing of surgical decompression in patients
with traumatic spinal cord injury (SCI) and central cord syndrome. Methods: A systematic …

Understanding exosomes: Part 2—Emerging leaders in regenerative medicine

RJ Miron, NE Estrin, A Sculean… - Periodontology 2000, 2024 - Wiley Online Library
Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with the ability to communicate with other tissues and cell types over long distances. Their …

Stem cell therapy for spinal cord injury

L Huang, C Fu, F **ong, C He, Q Wei - Cell transplantation, 2021 - journals.sagepub.com
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues,
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …

Concise review: bridging the gap: novel neuroregenerative and neuroprotective strategies in spinal cord injury

CS Ahuja, M Fehlings - Stem cells translational medicine, 2016 - academic.oup.com
Spinal cord injuries (SCIs) result in devastating lifelong disability for patients and their
families. The initial mechanical trauma is followed by a damaging secondary injury cascade …

An update of a clinical practice guideline for the management of patients with acute spinal cord injury: recommendations on the role and timing of decompressive …

MG Fehlings, LA Tetreault, L Hachem… - Global Spine …, 2024 - journals.sagepub.com
Study Design Clinical practice guideline development. Objectives Acute spinal cord injury
(SCI) can result in devastating motor, sensory, and autonomic impairment; loss of …

Timing of decompression in patients with acute spinal cord injury: a systematic review

JR Wilson, LA Tetreault, BK Kwon… - Global spine …, 2017 - journals.sagepub.com
Study Design: Systematic review. Objective: To conduct a systematic review and synthesis of
the literature to assess the comparative effectiveness, safety, and cost-effectiveness of early …