[HTML][HTML] Opportunities of connectomic neuromodulation
The process of altering neural activity–neuromodulation–has long been used to treat
patients with brain disorders and answer scientific questions. Deep brain stimulation in …
patients with brain disorders and answer scientific questions. Deep brain stimulation in …
[HTML][HTML] White matter tractography for neurosurgical planning: A topography-based review of the current state of the art
We perform a review of the literature in the field of white matter tractography for
neurosurgical planning, focusing on those works where tractography was correlated with …
neurosurgical planning, focusing on those works where tractography was correlated with …
Predicting optimal deep brain stimulation parameters for Parkinson's disease using functional MRI and machine learning
Commonly used for Parkinson's disease (PD), deep brain stimulation (DBS) produces
marked clinical benefits when optimized. However, assessing the large number of possible …
marked clinical benefits when optimized. However, assessing the large number of possible …
Lead-DBS v2: Towards a comprehensive pipeline for deep brain stimulation imaging
Deep brain stimulation (DBS) is a highly efficacious treatment option for movement disorders
and a growing number of other indications are investigated in clinical trials. To ensure …
and a growing number of other indications are investigated in clinical trials. To ensure …
Connectivity predicts deep brain stimulation outcome in P arkinson disease
Objective The benefit of deep brain stimulation (DBS) for Parkinson disease (PD) may
depend on connectivity between the stimulation site and other brain regions, but which …
depend on connectivity between the stimulation site and other brain regions, but which …
A unified connectomic target for deep brain stimulation in obsessive-compulsive disorder
Multiple surgical targets for treating obsessive-compulsive disorder with deep brain
stimulation (DBS) have been proposed. However, different targets may modulate the same …
stimulation (DBS) have been proposed. However, different targets may modulate the same …
Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson's disease
Objectives Firstly, to identify subthalamic region stimulation clusters that predict maximum
improvement in rigidity, bradykinesia and tremor, or emergence of side-effects; and …
improvement in rigidity, bradykinesia and tremor, or emergence of side-effects; and …
A brain network for deep brain stimulation induced cognitive decline in Parkinson's disease
Deep brain stimulation is an effective treatment for Parkinson's disease but can be
complicated by side-effects such as cognitive decline. There is often a delay before this side …
complicated by side-effects such as cognitive decline. There is often a delay before this side …
Toward personalized medicine in connectomic deep brain stimulation
At the group-level, deep brain stimulation leads to significant therapeutic benefit in a
multitude of neurological and neuropsychiatric disorders. At the single-patient level …
multitude of neurological and neuropsychiatric disorders. At the single-patient level …
The right superior frontal gyrus and individual variation in proactive control of impulsive response
A hallmark of cognitive control is the ability to rein in impulsive responses. Previously, we
used a Bayesian model to describe trial-by-trial likelihood of the stop signal or p (Stop) and …
used a Bayesian model to describe trial-by-trial likelihood of the stop signal or p (Stop) and …