Polyploidy in liver development, homeostasis and disease
R Donne, M Saroul-Aïnama, P Cordier… - Nature reviews …, 2020 - nature.com
Polyploidy (or whole-genome duplication) is the condition of having more than two basic
sets of chromosomes. Polyploidization is well tolerated in many species and can lead to …
sets of chromosomes. Polyploidization is well tolerated in many species and can lead to …
Uterine glands: developmental biology and functional roles in pregnancy
All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …
Polyploidy in tissue homeostasis and regeneration
JI Øvrebø, BA Edgar - Development, 2018 - journals.biologists.com
Polyploid cells, which contain multiple copies of the typically diploid genome, are
widespread in plants and animals. Polyploidization can be developmentally programmed or …
widespread in plants and animals. Polyploidization can be developmentally programmed or …
Embryo-derive TNF promotes decidualization via fibroblast activation
ST Chen, WW Shi, YQ Lin, ZS Yang, Y Wang, MY Li… - Elife, 2023 - elifesciences.org
Decidualization is a process in which endometrial stromal fibroblasts differentiate into
specialized secretory decidual cells and essential for the successful establishment of …
specialized secretory decidual cells and essential for the successful establishment of …
Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade
Cell proliferation is tightly controlled by inhibitors that block cell cycle progression until
growth signals relieve this inhibition, allowing cells to divide. In several tissues, including the …
growth signals relieve this inhibition, allowing cells to divide. In several tissues, including the …
The high concentration of progesterone is harmful for endometrial receptivity and decidualization
Progesterone is required for the establishment and maintenance of mammalian pregnancy
and widely used for conservative treatment of luteal phase deficiency in clinics. However …
and widely used for conservative treatment of luteal phase deficiency in clinics. However …
The mammalian decidual cell evolved from a cellular stress response
Among animal species, cell types vary greatly in terms of number and kind. The number of
cell types found within an organism differs considerably between species, and cell type …
cell types found within an organism differs considerably between species, and cell type …
IHH, SHH, and primary cilia mediate epithelial-stromal cross-talk during decidualization in mice
The establishment of pregnancy depends on interactions between the epithelial and stromal
cells of the endometrium that drive the decidual reaction that remodels the stroma and …
cells of the endometrium that drive the decidual reaction that remodels the stroma and …
BHPF exposure impairs mouse and human decidualization
ZY **, CK Liu, YQ Hong, YX Liang, L Liu… - Environmental Pollution, 2022 - Elsevier
Although BHPF has been widely used in plastic manufacturing as a substitute for BPA,
current evidence suggests that BHPF also causes harmful effects on reproduction. However …
current evidence suggests that BHPF also causes harmful effects on reproduction. However …
[HTML][HTML] E2F8 is a potential therapeutic target for hepatocellular carcinoma
Y Lv, J **ao, J Liu, F **ng - Journal of Cancer, 2017 - ncbi.nlm.nih.gov
E2F transcriptional factors are widely expressed in a number of tissues and organs,
possessing many regulatory functions related to cellular proliferation, differentiation, DNA …
possessing many regulatory functions related to cellular proliferation, differentiation, DNA …