In humans, cell fusion is restricted to only a few cell types under normal conditions. In the
placenta, cell fusion is a critical process for generating syncytiotrophoblast: the giant …

The capacity to integrate into the chromosomal DNA of germ-line cells has endowed
retroviruses with the potential to be vertically transmitted from generation to generation and …

Exosomes are extracellular vesicles that mediate intercellular communication and are
involved in several biological processes. The objective of our study was to determine …

Modulation of the activation status of immune cell populations during pregnancy depends on
placental villous cytotrophoblast (VCT) cells and the syncytiotrophoblast (STB). Failure in the …

Abstract Preeclampsia (PE), Hemolysis Elevated Liver Enzymes and Low Platelets (HELLP)‐
syndrome, and intrauterine growth restriction (IUGR) are associated with abnormal …

OBJECTIVES: To examine whether syncytin-1 has immune regulatory functions and is
carried by human placental exosomes. Further, to examine whether corticotropin-releasing …

Endogenous retroviruses represent about 8% of the human genome and belong to the
superfamily of transposable and retrotransposable genetic elements. Altogether, these …

Extracellular vesicles (EVs)─ including exosomes and microvesicles─ are involved in cell–
cell communication. EVs encapsulate different types of molecules such as proteins or …

Endometrial carcinomas (EnCa) predominantly represent a steroid hormone-driven tumor
initiated from prestages. The human endogenous retrovirus HERV-W envelope gene …

Retroviral envelopes are pathogenic glycoproteins which cause neuroinflammation,
neurodegeneration, and endoplasmic reticulum stress responses. The human endogenous …