Early adversity and the neotenous human brain

N Tottenham - Biological psychiatry, 2020 - Elsevier
Human brain development is optimized to learn from environmental cues. The protracted
development of the cortex and its connections with subcortical targets has been argued to …

Neurobiological markers of resilience to early-life adversity during adolescence

ASM Leal, JA Silvers - Biological Psychiatry: Cognitive Neuroscience and …, 2021 - Elsevier
Early-life adversity (ELA) exposure (eg, trauma, abuse, neglect, or institutional care) is a
precursor to poor physical and mental health outcomes and is implicated in 30% of adult …

Prenatal socioeconomic status and social support are associated with neonatal brain morphology, toddler language and psychiatric symptoms

MN Spann, R Bansal, X Hao, TS Rosen… - Child …, 2020 - Taylor & Francis
Few studies have assessed the association of parental socioeconomic status (SES) with
brain measures in neonates, at a time when exposure to the postnatal environment is …

Social connectedness and negative affect uniquely explain individual differences in response to emotional ambiguity

M Neta, RL Brock - Scientific Reports, 2021 - nature.com
Negativity bias is not only central to mood and anxiety disorders, but can powerfully impact
our decision-making across domains (eg, financial, medical, social). This project builds on …

Attachment and alexithymia predict emotional–behavioural problems of institutionalized, late‐adopted and community adolescents: An explorative multi‐informant …

S Muzi, CS Pace - Clinical psychology & psychotherapy, 2023 - Wiley Online Library
Objective Compared to community adolescents (COM), adolescents placed in residential
care (RC) or late adopted (LA) appear to show more emotional–behavioural problems. They …

Early life adversity is associated with greater similarity in neural representations of ambiguous and threatening stimuli

NM Saragosa-Harris, JFG Moreira… - Development and …, 2024 - cambridge.org
Exposure to early life adversity (ELA) is hypothesized to sensitize threat-responsive neural
circuitry. This may lead individuals to overestimate threat in the face of ambiguity, a cognitive …

Neural meaning making, prediction, and prefrontal–subcortical development following early adverse caregiving

N Tottenham - Development and psychopathology, 2020 - cambridge.org
Early adversities that are caregiving-related (crEAs) are associated with a significantly
increased risk for mental health problems. Recent neuroscientific advances have revealed …

Multiple facets of attachment in residential-care, late adopted, and community adolescents: an interview-based comparative study

S Muzi, CS Pace - Attachment & Human Development, 2022 - Taylor & Francis
ABSTRACT In this study, 117 adolescents (12–19 years) from three groups (39 each), two
groups from adverse caregiving environments as placed in residential-care (RC; ie …

Neural representations of ambiguous affective stimuli and resilience to anxiety in emerging adults

NM Saragosa-Harris, JFG Moreira, YH Waizman… - Biological …, 2023 - Elsevier
The tendency to interpret ambiguous stimuli as threatening has been associated with a
range of anxiety disorders. Responses to ambiguity may be particularly relevant to mental …

Exploring valence bias as a metric for frontoamygdalar connectivity and depressive symptoms in childhood

NM Petro, N Tottenham, M Neta - Developmental …, 2021 - Wiley Online Library
Negativity bias is a core feature of depression that is associated with dysfunctional
frontoamygdalar connectivity; this pathway is associated with emotion regulation and …