How biology handles nitrite
Nitrite is one of the players in the broad nitrogen biogeochemical cycle. This nitrogen oxo-
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …
Function and evolution of vertebrate globins
Globins are haem‐proteins that bind O2 and thus play an important role in the animal's
respiration and oxidative energy production. However, globins may also have other …
respiration and oxidative energy production. However, globins may also have other …
Human neuroglobin functions as a redox-regulated nitrite reductase
Neuroglobin is a highly conserved hemoprotein of uncertain physiological function that
evolved from a common ancestor to hemoglobin and myoglobin. It possesses a six …
evolved from a common ancestor to hemoglobin and myoglobin. It possesses a six …
Structure and reactivity of hexacoordinate hemoglobins
The heme prosthetic group in hemoglobins is most often attached to the globin through
coordination of either one or two histidine side chains. Those proteins with one histidine …
coordination of either one or two histidine side chains. Those proteins with one histidine …
Neuroglobin: From structure to function in health and disease
In 2000, the third member of the globin family was discovered in human and mouse brain
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …
and named neuroglobin (Ngb). Ngb is a monomeric 3/3 globin structurally similar to …
Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax
A Avivi, F Gerlach, A Joel, S Reuss… - Proceedings of the …, 2010 - National Acad Sciences
The subterranean mole rat Spalax is an excellent model for studying adaptation of a
mammal toward chronic environmental hypoxia. Neuroglobin (Ngb) and cytoglobin (Cygb) …
mammal toward chronic environmental hypoxia. Neuroglobin (Ngb) and cytoglobin (Cygb) …
Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa
The study of inherited retinal diseases has advanced our knowledge of the cellular and
molecular mechanisms involved in sensory neural signaling. Dysfunction of two specific …
molecular mechanisms involved in sensory neural signaling. Dysfunction of two specific …
Neuroglobin protects astroglial cells from hydrogen peroxide‐induced oxidative stress and apoptotic cell death
F Amri, I Ghouili, M Amri, A Carrier… - Journal of …, 2017 - Wiley Online Library
Oxidative stress, resulting from accumulation of reactive oxygen species, plays a critical role
in astroglial cell death occurring in diverse neuropathological conditions. Numerous studies …
in astroglial cell death occurring in diverse neuropathological conditions. Numerous studies …
Neuroglobin protects neurons against oxidative stress in global ischemia
RC Li, SZ Guo, SK Lee, D Gozal - Journal of Cerebral Blood …, 2010 - journals.sagepub.com
Neuroglobin (Ngb) is a recently discovered globin that affords protection against
hypoxic/ischemic-induced cell injury in brain. Hypoxic/ischemic injury is associated with …
hypoxic/ischemic-induced cell injury in brain. Hypoxic/ischemic injury is associated with …
Neuroglobin, clues to function and mechanism
C Exertier, LC Montemiglio, I Freda, E Gugole… - Molecular Aspects of …, 2022 - Elsevier
Neuroglobin is expressed in vertebrate brain and belongs to a branch of the globin family
that diverged early in evolution. Sequence conservation and presence in nervous cells of …
that diverged early in evolution. Sequence conservation and presence in nervous cells of …