Hyperconnectivity is a fundamental response to neurological disruption.

FG Hillary, CA Roman, U Venkatesan… - …, 2015 - psycnet.apa.org
Objective: In the cognitive and clinical neurosciences, the past decade has been marked by
dramatic growth in a literature examining brain “connectivity” using noninvasive methods …

Medial temporal lobe disconnection and hyperexcitability across Alzheimer's disease stages

L Pasquini, F Rahmani… - Journal of …, 2019 - content.iospress.com
The posteromedial cortex (PMC) and medial temporal lobes (MTL) are two brain regions
particularly vulnerable in Alzheimer's disease (AD). We have reviewed the spatiotemporal …

Altered static and dynamic functional network connectivity in Alzheimer's disease and subcortical ischemic vascular disease: shared and specific brain connectivity …

Z Fu, A Caprihan, J Chen, Y Du, JC Adair… - Human brain …, 2019 - Wiley Online Library
Subcortical ischemic vascular disease (SIVD) is a major subtype of vascular dementia with
features that overlap clinically with Alzheimer's disease (AD), confounding diagnosis …

Altered directed functional connectivity of the hippocampus in mild cognitive impairment and Alzheimer's disease: a resting-state fMRI study

J Xue, H Guo, Y Gao, X Wang, H Cui, Z Chen… - Frontiers in aging …, 2019 - frontiersin.org
The hippocampus is generally reported as one of the regions most impacted by Alzheimer's
disease (AD) and is closely associated with memory function and orientation. Undirected …

Sex differences in brain functional connectivity of hippocampus in mild cognitive impairment

J Williamson, A Yabluchanskiy, P Mukli… - Frontiers in aging …, 2022 - frontiersin.org
Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's Disease (AD). Prior
research shows that females are more impacted by MCI than males. On average females …

The lower hippocampus global connectivity, the higher its local metabolism in Alzheimer disease

M Tahmasian, L Pasquini, M Scherr, C Meng… - Neurology, 2015 - AAN Enterprises
Objectives: Based on the hippocampus disconnection hypothesis in Alzheimer disease
(AD), which postulates that uncoupling from cortical inputs contributes to disinhibition-like …

The inclusion of functional connectivity information into fMRI-based neurofeedback improves its efficacy in the reduction of cigarette cravings

DY Kim, SS Yoo, M Tegethoff… - Journal of cognitive …, 2015 - direct.mit.edu
Real-time fMRI (rtfMRI) neurofeedback (NF) facilitates volitional control over brain activity
and the modulation of associated mental functions. The NF signals of traditional rtfMRI-NF …

Diminished posterior precuneus connectivity with the default mode network differentiates normal aging from Alzheimer's disease

BL Klaassens, JMA van Gerven… - Frontiers in aging …, 2017 - frontiersin.org
Both normal aging and Alzheimer's disease (AD) have been associated with a reduction in
functional brain connectivity. It is unknown how connectivity patterns due to aging and AD …