This study explores the roles of genome copy number abnormalities (CNAs) in breast cancer
pathophysiology by identifying associations between recurrent CNAs, gene expression, and …

Following a previous genome-wide association study (GWAS 1) including 744 cases and
895 controls, we analyzed genome-wide association data from a new cohort of Han Chinese …

Breast Cancer is a complex disease characterized by the occurrence of multiple molecular
alterations. Currently, some molecular markers are in use for breast cancer diagnostic …

Epigenetic and epitranscriptomic networks have important functions in maintaining the
pluripotency of embryonic stem cells (ESCs) and somatic cell reprogramming. However, the …

Women with dense breasts have an increased lifetime risk of malignancy that has been
attributed to a higher epithelial density. Quantitative proteomics, collagen analysis, and …

The recently described oncogene ZNF217 belongs to a chromosomal region that is
frequently amplified in human cancers. Recent findings have revealed that alternative …

The Krüppel-like zinc finger protein ZNF217 is a candidate oncogene in breast cancer. In
this study, we showed that high levels of expression of ZNF217 mRNA are associated with …

Background Oncogene amplification and overexpression occur in tumor cells. Amplification
status may provide diagnostic and prognostic information and may lead to new treatment …

AT-rich interactive domain 1A (ARID1A) is a subunit of switch/sucrose non-fermentable
(SWI/SNF) complex. Recently, alterations of ARID1A gene, phosphatidylinositol 3-kinase …

Purpose: Amplification of chromosomal region 20q13 occurs in breast cancer but remains
poorly characterized. Experimental Design: To establish the frequency of 20q13 …