Force measurements with the atomic force microscope: Technique, interpretation and applications

HJ Butt, B Cappella, M Kappl - Surface science reports, 2005 - Elsevier
The atomic force microscope (AFM) is not only a tool to image the topography of solid
surfaces at high resolution. It can also be used to measure force-versus-distance curves …

Scratching the surface: fundamental investigations of tribology with atomic force microscopy

RW Carpick, M Salmeron - Chemical reviews, 1997 - ACS Publications
A few years after the invention of the scanning tunneling microscope (STM), the atomic force
microscope (AFM) was developed. 1 Instead of measuring tunneling current, a new physical …

Micromechanical cantilever-based biosensors

R Raiteri, M Grattarola, HJ Butt, P Skládal - Sensors and Actuators B …, 2001 - Elsevier
The merging of silicon microfabrication techniques with surface functionalization
biochemistry offers new exciting opportunities in develo** microscopic biomedical …

Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy

MDA Norman, SA Ferreira, GM Jowett, L Bozec… - Nature …, 2021 - nature.com
Growing interest in exploring mechanically mediated biological phenomena has resulted in
cell culture substrates and 3D matrices with variable stiffnesses becoming standard tools in …

[HTML][HTML] Mechanical properties of collagen fibrils

MPE Wenger, L Bozec, MA Horton, P Mesquida - Biophysical journal, 2007 - cell.com
The formation of collagen fibers from staggered subfibrils still lacks a universally accepted
model. Determining the mechanical properties of single collagen fibrils (diameter 50 …

Dynamic elastic modulus of porcine articular cartilage determined at two different levels of tissue organization by indentation-type atomic force microscopy

M Stolz, R Raiteri, AU Daniels, MR VanLandingham… - Biophysical journal, 2004 - cell.com
Cartilage stiffness was measured ex vivo at the micrometer and nanometer scales to explore
structure-mechanical property relationships at smaller scales than has been done …

Spring constant calibration of atomic force microscope cantilevers of arbitrary shape

JE Sader, JA Sanelli, BD Adamson, JP Monty… - Review of Scientific …, 2012 - pubs.aip.org
for a rectangular cantilever requires measurement of the resonant frequency and quality
factor in fluid (typically air), and knowledge of its plan view dimensions. This intrinsically …

Measuring the spring constant of atomic force microscope cantilevers: thermal fluctuations and other methods

R Levy, M Maaloum - Nanotechnology, 2001 - iopscience.iop.org
Abstract Knowledge of the interaction forces between surfaces gained using an atomic force
microscope (AFM) is crucial in a variety of industrial and scientific applications and …

[HTML][HTML] Single molecule force spectroscopy in biology using the atomic force microscope

J Zlatanova, SM Lindsay, SH Leuba - Progress in biophysics and molecular …, 2000 - Elsevier
The importance of forces in biology has been recognized for quite a while but only in the
past decade have we acquired instrumentation and methodology to directly measure …

Robust strategies for automated AFM force curve analysis—I. Non-adhesive indentation of soft, inhomogeneous materials

DC Lin, EK Dimitriadis, F Horkay - 2007 - asmedigitalcollection.asme.org
The atomic force microscope (AFM) has found wide applicability as a nanoindentation tool to
measure local elastic properties of soft materials. An automated approach to the processing …