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[HTML][HTML] Indole: A promising scaffold for the discovery and development of potential anti-tubercular agents
Indole-containing small molecules have been reported to have diverse pharmacological
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …
In vitro anti-tuberculosis effect of probiotic Lacticaseibacillus rhamnosus PMC203 isolated from vaginal microbiota
Abstract Mycobacterium tuberculosis (M. tb), the etiological agent of tuberculosis (TB), poses
a severe challenge for public health and remains the number one cause of death as a single …
a severe challenge for public health and remains the number one cause of death as a single …
Synthesis, structural investigations, DFT calculations, and molecular docking studies of novel 2-(substituted-aryloxymethyl)-5-(pyridin-4-yl)-1, 3, 4-oxadiazoles: Highly …
M Datar, R Dhanwad, M Javeed… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Abstract We report derivatives of 2, 5-disubstituted-1, 3, 4-oxadiazole as powerful anti-TB
and antioxidant compounds. Using substituted aryloxy acetic acids (2a–f) and isoniazid (3) …
and antioxidant compounds. Using substituted aryloxy acetic acids (2a–f) and isoniazid (3) …
Recent efforts in the development of glycoconjugate vaccine and available treatment for tuberculosis
Tuberculosis (TB) continues to pose a grave threat to global health, despite relentless
eradication efforts. In 1882, Robert Koch discovered that Mycobacterium tuberculosis is the …
eradication efforts. In 1882, Robert Koch discovered that Mycobacterium tuberculosis is the …
Synthesis of alkynylated 1, 2, 4-oxadiazole/1, 2, 3-1H-triazole glycoconjugates: Discovering new compounds for use in chemotherapy against lung carcinoma and …
VNM de Oliveira, CF do Amaral Moura… - European Journal of …, 2021 - Elsevier
A total of forty-three compounds were synthesized, including thirty-two new ones. Among
those compounds, seventeen were selected and tested on human tumor cell lines: PC-3 …
those compounds, seventeen were selected and tested on human tumor cell lines: PC-3 …
Nitrothiazole‐Thiazolidinone Hybrids: Synthesis and in Vitro Antimicrobial Evaluation
Herein we report the synthesis of novel compounds inspired by the antimicrobial activities of
nitroazole and thiazolidin‐4‐one based compounds reported in the literature. Target …
nitroazole and thiazolidin‐4‐one based compounds reported in the literature. Target …
[PDF][PDF] Identification of Probiotic Strains with Anti-Tuberculosis Activity and Their Characterization as Potential Therapeutic Agents
Tuberculosis (TB) remains a global health crisis, with the emergence of multidrugresistant
strains necessitating the development of novel therapeutic strategies. Approximately one …
strains necessitating the development of novel therapeutic strategies. Approximately one …
[HTML][HTML] MDN-6, a Possible Therapeutic Candidate for Multidrug-Resistant and Extensively Drug-Resistant Mycobacterium tuberculosis
Background: The rise of antibiotic-resistant Mycobacterium tuberculosis strains has
accelerated the hunt for novel drugs for tuberculosis (TB). Objectives: This study identified a …
accelerated the hunt for novel drugs for tuberculosis (TB). Objectives: This study identified a …