Deuterium MR spectroscopy: potential applications in oncology research

AGV Bitencourt, A Bhowmik, EFDL Marcal Filho… - BJR| Open, 2024 - academic.oup.com
Metabolic imaging in clinical practice has long relied on PET with fluorodeoxyglucose
(FDG), a radioactive tracer. However, this conventional method presents inherent limitations …

Increased cerebral lactate levels in adults with autism spectrum disorders compared to non-autistic controls: a magnetic resonance spectroscopy study

S Maier, K Nickel, T Lange, G Oeltzschner, M Dacko… - Molecular Autism, 2023 - Springer
Introduction Autism spectrum disorder (ASD) encompasses a heterogeneous group with
varied phenotypes and etiologies. Identifying pathogenic subgroups could facilitate targeted …

Repeatability of Lac+ measurements in healthy human brain at 3 T

R Armbruster, N Wilson, MA Elliott, F Liu… - NMR in …, 2024 - Wiley Online Library
Purpose In vivo quantification of lactate has numerous applications in studying the
pathology of both cerebral and musculoskeletal systems. Due to its low concentration (~ 0.5 …

Evaluation of Glutathione T2 in the Human Brain Using J‐Difference MRS at 3 T: Multicenter Multivendor Study

G Choi, S Kim, R Noeske, JE Moore… - NMR in …, 2025 - Wiley Online Library
The need to quantify brain glutathione (GSH) accurately by J‐difference spectroscopy has
stimulated assessment of the TE effects on GSH edited signals at the popular field strength 3 …

[HTML][HTML] Improving Brain Metabolite Detection with a Combined Low-Rank Approximation and Denoising Diffusion Probabilistic Model Approach

YJ Jeon, KM Nam, SE Park, HM Baek - Bioengineering, 2024 - mdpi.com
In vivo proton magnetic resonance spectroscopy (MRS) is a noninvasive technique for
monitoring brain metabolites. However, it is challenged by a low signal-to-noise ratio (SNR) …

Optimization of the flip angles of narrow‐band editing pulses in J‐difference edited MRS of lactate at 3T

JE Moore, RK Robison, J Hu… - Magnetic …, 2024 - Wiley Online Library
Purpose Application of highly selective editing RF pulses provides a means of minimizing co‐
editing of contaminants in J‐difference MRS (MEGA), but it causes reduction in editing yield …