[HTML][HTML] CD4+ T cell memory
Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II–
peptide complexes to control phagosomal infections, help B cells, regulate tissue …
peptide complexes to control phagosomal infections, help B cells, regulate tissue …
Central memory and effector memory T cell subsets: function, generation, and maintenance
The memory T cell pool functions as a dynamic repository of antigen-experienced T
lymphocytes that accumulate over the lifetime of the individual. Recent studies indicate that …
lymphocytes that accumulate over the lifetime of the individual. Recent studies indicate that …
L-arginine modulates T cell metabolism and enhances survival and anti-tumor activity
Metabolic activity is intimately linked to T cell fate and function. Using high-resolution mass
spectrometry, we generated dynamic metabolome and proteome profiles of human primary …
spectrometry, we generated dynamic metabolome and proteome profiles of human primary …
Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells
Abstract Interleukin 17 (IL-17)–producing T helper cells (TH-17 cells) have been
characterized in mice as a distinct subset of effector cells, but their identity and properties in …
characterized in mice as a distinct subset of effector cells, but their identity and properties in …
Transforming growth factor-β'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset
M Veldhoen, C Uyttenhove, J Van Snick, H Helmby… - Nature …, 2008 - nature.com
Since the discovery of T helper type 1 and type 2 effector T cell subsets 20 years ago,
inducible regulatory T cells and interleukin 17 (IL-17)-producing T helper cells have been …
inducible regulatory T cells and interleukin 17 (IL-17)-producing T helper cells have been …
Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
Abstract IL-17-producing CD4+ T helper cells (TH17) have been extensively investigated in
mouse models of autoimmunity. However, the requirements for differentiation and the …
mouse models of autoimmunity. However, the requirements for differentiation and the …
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
Abstract Interleukin 22 (IL-22) is a cytokine produced by the TH-17 lineage of helper T cells
and NK-22 subset of natural killer cells that acts on epithelial cells and keratinocytes and …
and NK-22 subset of natural killer cells that acts on epithelial cells and keratinocytes and …
The era of cytotoxic CD4 T cells
M Cenerenti, M Saillard, P Romero… - Frontiers in …, 2022 - frontiersin.org
In 1986, Mosmann and Coffman identified 2 functionally distinct subsets of activated CD4 T
cells, Th1 and Th2 cells, being key in distinct T cell mediated responses. Over the past three …
cells, Th1 and Th2 cells, being key in distinct T cell mediated responses. Over the past three …
Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
The mechanisms by which immune responses to nonpathogenic environmental antigens
lead to either allergy or nonharmful immunity are unknown. Single allergen-specific T cells …
lead to either allergy or nonharmful immunity are unknown. Single allergen-specific T cells …
T cells in patients with narcolepsy target self-antigens of hypocretin neurons
Narcolepsy is a chronic sleep disorder caused by the loss of neurons that produce
hypocretin. The close association with HLA-DQB1* 06: 02, evidence for immune …
hypocretin. The close association with HLA-DQB1* 06: 02, evidence for immune …