[HTML][HTML] Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics

Y Gupta, OV Savytskyi, M Coban, A Venugopal… - Molecular Aspects of …, 2023 - Elsevier
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …

Health effects of vitamin D supplementation: lessons learned from randomized controlled trials and mendelian randomization studies

R Bouillon, MS LeBoff, RE Neale - Journal of Bone and Mineral …, 2023 - academic.oup.com
Vitamin D plays an important role in calcium homeostasis and many cellular processes.
Although vitamin D supplements are widely recommended for community‐dwelling adults …

Low vitamin D levels predict outcomes of COVID-19 in patients with both severe and non-severe disease at hospitalization

L Di Filippo, M Uygur, M Locatelli, F Nannipieri, S Frara… - Endocrine, 2023 - Springer
Purpose Low vitamin D in COVID-19 have been related to worse outcomes. However, most
of the studies conducted so far were not-controlled and retrospective, including biases …

Involvement of the secosteroid vitamin D in autoimmune rheumatic diseases and COVID-19

M Cutolo, V Smith, S Paolino, E Gotelli - Nature Reviews Rheumatology, 2023 - nature.com
Evidence supporting the extra-skeletal role of vitamin D in modulating immune responses is
centred on the effects of its final metabolite, 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3, also …

Consensus and controversial aspects of vitamin D and COVID-19

JP Bilezikian, N Binkley, HF De Luca… - The Journal of …, 2023 - academic.oup.com
Objective This work aims to review and discuss controversial topics in the field of vitamin D,
SARS-CoV-2 infection, and COVID-19. Methods The International Conferences …

Vitamin D endocrine system and COVID-19: treatment with calcifediol

JM Quesada-Gomez, J Lopez-Miranda… - Nutrients, 2022 - mdpi.com
The COVID-19 pandemic is the greatest challenge facing modern medicine and public
health systems. The viral evolution of SARS-CoV-2, with the emergence of new variants with …

Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients

C Loucera, M Peña-Chilet, M Esteban-Medina… - Scientific reports, 2021 - nature.com
COVID-19 is a major worldwide health problem because of acute respiratory distress
syndrome, and mortality. Several lines of evidence have suggested a relationship between …

[HTML][HTML] The sex and gender dimensions of COVID-19: A narrative review of the potential underlying factors

JT Mourosi, S Anwar, MJ Hosen - Infection, Genetics and Evolution, 2022 - Elsevier
Multiple lines of evidence indicate that the male sex is a significant risk factor for severe
disease and mortality due to coronavirus disease 2019 (COVID-19). However, the precise …

Vitamin D3 and COVID-19 outcomes: an umbrella review of systematic reviews and meta-analyses

F Petrelli, S Oldani, K Borgonovo, M Cabiddu… - Antioxidants, 2023 - mdpi.com
Background: The immune system (innate and adaptive) is influenced by vitamin D3, which
affects gene expression and inflammatory pathways. An umbrella review was conducted to …

EMAS position statement: Vitamin D and menopausal health

P Anagnostis, S Livadas, DG Goulis, S Bretz, I Ceausu… - Maturitas, 2023 - Elsevier
Introduction There is increasing evidence that vitamin D has widespread tissue effects. In
addition to osteoporosis, vitamin D deficiency has been associated with cardiovascular …