Pancreatic beta-cell death has been established as a critical mediator in the progression of
type 1 and type 2 diabetes mellitus. Beta-cell death is associated with exacerbating …

A delicate balance between programmed cell death and proliferation of intestinal epithelial
cells (IEC) exists in the gut to maintain homeostasis. Homeostatic cell death programs such …

Objective Receptor-interacting protein kinase 1 (RIPK1) orchestrates the decision between
cell survival and cell death in response to tumor necrosis factor (TNF) and other cytokines …

Abstract Objectives Type 1 diabetes (T1D) is caused by progressive immune-mediated loss
of insulin-producing β-cells. Inflammation is detrimental to β-cell function and survival …

Background and aims Hepatitis B virus (HBV)-associated liver cirrhosis (LC), a common
condition with high incidence and mortality rates, is often associated with diabetes mellitus …

Cellular responses to TNF are inherently heterogeneous within an isogenic cell population
and across different cell types. TNF promotes cell survival by activating pro-inflammatory NF …

Type 1 Diabetes (T1D) is caused by a combination of genetic and environmental factors that
trigger autoimmune-mediated destruction of pancreatic β-cells. Defects in β-cell stress …

Aim To characterize the exosomal miRNA profiles of latent autoimmune diabetes in adults
(LADA) and evaluate the biomarker potential of selected miRNAs to distinguish LADA from …

Aim Our study aims to identify novel non-coding RNA-mRNA regulatory networks associated
with β-cell dysfunction and compensatory responses in obesity-related diabetes. Methods …

Nonalcoholic fatty liver disease (NAFLD) is the most prevalent type of chronic liver disease.
However, the disease is underappreciated as a remarkable chronic disorder as there are …