Microglia are resident immune cells in the central nervous system, playing critical roles in
brain development and homeostasis. Increasing evidence has implicated microglia …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …

Galectin-3, an attractive molecule of innate immunity, has been reported to be involved in
the neuroinflammatory diseases. However, the role of Galectin-3 in autoimmune uveitis is …

For decades, it has been widely believed that the blood–brain barrier (BBB) provides an
immune privileged environment in the central nervous system (CNS) by blocking peripheral …

Immunopsychiatric field has rapidly accumulated evidence demonstrating the involvement of
both innate and adaptive immune components in psychotic disorders such as …

Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Early-life stress (ELS) leads to increased vulnerability to psychiatric disorders including
depression later in life. Neuroinflammatory processes have been implicated in ELS-induced …

Increasing evidence supports the notion that neuroinflammation plays a critical role in the
etiology of major depressive disorder (MDD), at least in a subset of patients. By virtue of their …

Modulation of the inflammasome NLRP3 and SIRT1 are new combat strategy for brain injury
protection. The inflammasome activates proinflammatory cytokines releasing interleukin-1β …

Background Postoperative cognitive dysfunction (POCD) is a neurological complication
occurring after anesthesia and surgery. Neuroinflammation plays a critical role in the …