Identifying rare genetic variants in 21 highly multiplex autism families: the role of diagnosis and autistic traits

RP More, V Warrier, H Brunel, C Buckingham… - Molecular …, 2023 - nature.com
Autism is a highly heritable, heterogeneous, neurodevelopmental condition. Large-scale
genetic studies, predominantly focussing on simplex families and clinical diagnoses of …

Structural models of genome-wide covariance identify multiple common dimensions in autism

L De Hoyos, MT Barendse, F Schlag… - Nature …, 2024 - nature.com
Common genetic variation has been associated with multiple phenotypic features in Autism
Spectrum Disorder (ASD). However, our knowledge of shared genetic factor structures …

Serotonin signaling in the enteric nervous system and connection to autism spectrum disorder: a translational mathematical model

I Kareva - Applied Sciences, 2023 - mdpi.com
While the causes of autism spectrum disorder (ASD) remain unclear, some studies have
shown that serotonin-mediated effects on the enteric nervous system (ENS) correlate with an …