Stem cell fate is closely intertwined with microenvironmental and endogenous cues within
the body. Recapitulating this dynamic environment ex vivo can be achieved through …

The inherently toxic nature of chemotherapy drugs is essential for them to kill cancer cells
but is also the source of the detrimental side effects experienced by patients. One strategy to …

Efficient intracellular drugs delivery and accumulation are the key determinant for
overcoming tumor multidrug resistance (MDR). To realize this purpose, dual-pH responsive …

A multifunctional prodrug, designated as TPP‐L‐GEM, is fabricated to realize image‐guided
in situ tumor photodynamic therapy (PDT) with red light activatable chemotherapy …

For the purpose of this review, active targeting in cancer research encompasses strategies
wherein a ligand for a cell surface receptor expressed on tumor cells is used to deliver a …

Advances in cancer treatment have greatly improved survival rates of children with cancer.
However, these same chemotherapeutic or radiologic treatments may result in long-term …

Background Doxorubicin has a broad spectrum of anticancer activity, but its clinical
application is limited due to serious side effects. The aim of this study was to explore a novel …

Cancer remains a global health burden prompting affordable, target-oriented, and safe
chemotherapeutic agents to reduce its incidence rate worldwide. In this study, a rapid, cost …

Simple Summary Cancer is among the leading causes of death, and cancer therapy suffers
from many drawbacks, the lack of selectivity being most noteworthy. In this review, we …

Doxorubicin (Dox) is a hydrophilic anticancer drug that has short retention time due to the
efficient efflux in some cancer cells (eg, ovarian adenocarcinoma SK-OV-3). Cyclic [W (RW) …