Alternative splicing of pre-mRNA is an essential post-and co-transcriptional mechanism of
gene expression regulation that produces multiple mature mRNA transcripts from a single …

Splicing of precursor messenger RNA (pre-mRNA) in yeast is executed by the spliceosome,
which consists of five small nuclear ribonucleoproteins (snRNPs), NTC (nineteen complex) …

Each cycle of pre–messenger RNA splicing, carried out by the spliceosome, comprises two
sequential transesterification reactions, which result in the removal of an intron and the …

The human spliceosome is a large ribonucleoprotein complex that catalyzes pre-mRNA
splicing. It consists of five snRNAs and more than 200 proteins. Because of this complexity …

In spliceosomes, dynamic RNA/RNA and RNA/protein interactions position the pre-mRNA
substrate for the two chemical steps of splicing. Not all of these interactions have been …

Patulin (PAT), mainly produced by Penicillium expansum, is a potential threat to health. In
recent years, PAT removal using antagonistic yeasts has become a hot research topic …

Among men, prostate cancer (PCa) is the second most frequently diagnosed cancer subtype
and has demonstrated a high degree of prevalence globally. BUD31, also known as …

Recent studies revealed that a significant fraction of any given proteome is presented by
proteins that do not have unique 3D structures as a whole or in significant parts. These …

Pre-mRNA splicing is an essential step in gene expression that removes intron sequences
efficiently and accurately to produce a mature mRNA for translation. It is the large and …

The yeast Bud31 protein, a Prp19 complex (NTC) member, aids spliceosome assembly and
thus promotes efficient pre-mRNA splicing. The bud31 null cells show mild budding …