Oral microbiota in human systematic diseases

X Peng, L Cheng, Y You, C Tang, B Ren, Y Li… - International journal of …, 2022 - nature.com
Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The
dynamic oral microbiota cooperates with the host to reflect the information and status of …

Periodontal disease: the good, the bad, and the unknown

LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

The oral microbiota: community composition, influencing factors, pathogenesis, and interventions

X Li, Y Liu, X Yang, C Li, Z Song - Frontiers in microbiology, 2022 - frontiersin.org
The human oral cavity provides a habitat for oral microbial communities. The complexity of
its anatomical structure, its connectivity to the outside, and its moist environment contribute …

The bidirectional relationship between periodontal disease and diabetes mellitus—A review

I Păunică, M Giurgiu, AS Dumitriu, S Păunică… - Diagnostics, 2023 - mdpi.com
Periodontitis is a chronic inflammatory disease caused by the presence of a bacterial biofilm
known as dental plaque. This biofilm affects the supporting apparatus of the teeth, especially …

[HTML][HTML] The oralome and its dysbiosis: New insights into oral microbiome-host interactions

A Radaic, YL Kapila - Computational and structural biotechnology journal, 2021 - Elsevier
The oralome is the summary of the dynamic interactions orchestrated between the
ecological community of oral microorganisms (comprised of up to approximately 1000 …

The cytokine network involved in the host immune response to periodontitis

W Pan, Q Wang, Q Chen - International journal of oral science, 2019 - nature.com
Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue
in the periodontal region. Although dysbiosis of the local microbial community initiates local …

Oral microbiota in human health and disease: A perspective

L Santacroce, PC Passarelli… - Experimental …, 2023 - journals.sagepub.com
The evolution of medical knowledge about oral microbiota has increased awareness of its
important role for the entire human body health. A wide range of microbial species …

Injectable hydrogels with high drug loading through B–N coordination and ROS-triggered drug release for efficient treatment of chronic periodontitis in diabetic rats

X Zhao, Y Yang, J Yu, R Ding, D Pei, Y Zhang, G He… - Biomaterials, 2022 - Elsevier
The clinical management of chronic periodontitis with diabetes mellitus (CPDM) is a long-
standing thorny issue. The excessive production of reactive oxygen species (ROS) is one of …

[HTML][HTML] Th17 cells and the IL-23/IL-17 axis in the pathogenesis of periodontitis and immune-mediated inflammatory diseases

K Bunte, T Beikler - International journal of molecular sciences, 2019 - mdpi.com
Innate immunity represents the semi-specific first line of defense and provides the initial host
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …

The bacterial connection between the oral cavity and the gut diseases

S Kitamoto, H Nagao-Kitamoto, R Hein… - Journal of dental …, 2020 - journals.sagepub.com
More than 100 trillion symbiotic microorganisms constitutively colonize throughout the
human body, including the oral cavity, the skin, and the gastrointestinal tract. The oral cavity …