The predominant role of IL-6 in cancer is its key promotion of tumour growth. IL-6 binds IL-6
receptor (IL-6R) and the membrane-bound glycoprotein gp130. The complex I-6/IL …

Emerging evidence reveals that adipose tissue-associated inflammation is a main
mechanism whereby obesity promotes colorectal cancer risk and progression. Increased …

Tumor-associated macrophages mediate the link between inflammation and cancer
progression. Here, we showed that macrophage-derived soluble factors induce canonical …

The association between obesity and colorectal neoplasia may be mediated by
inflammation. Circulating levels of C-reactive protein (CRP), interleukin-6 (IL-6), and tumor …

Objective We investigated the associations of circulating C-reactive protein (CRP) and
interleukin-6 (IL-6) with cancer risk. Methods We examined the associations of CRP and IL-6 …

Mounting evidence supports the tenet that innate immune responses to luminal microbes
participate in the development of gastrointestinal malignancies. The gastrointestinal tract is …

C‐reactive protein is a sensitive but nonspecific systemic marker of inflammation. Several
prospective studies have investigated the association of prediagnostic circulating C‐reactive …

Cancer is the primary cause of death in economically developed countries and the second
leading cause in develo** countries. Colorectal cancer (CRC) is the third most common …

Vitamin D and calcium affect several pathways involved in inflammation, tumor growth, and
immune surveillance relevant to carcinogenesis. Also, epidemiologic evidence indicates that …

The recurrence of colorectal polyps is caused by various factors and leads to the
carcinogenesis of colorectal cancer, which ranks third in incidence and fourth in mortality …