Application of noninvasive vagal nerve stimulation to stress-related psychiatric disorders

JD Bremner, NZ Gurel, MT Wittbrodt… - Journal of personalized …, 2020 - mdpi.com
Background: Vagal Nerve Stimulation (VNS) has been shown to be efficacious for the
treatment of depression, but to date, VNS devices have required surgical implantation, which …

Acute and long-term effects of COVID-19 on brain and mental health: A narrative review

JD Bremner, SJ Russo, R Gallagher… - Brain, behavior, and …, 2024 - Elsevier
Background COVID infection has been associated with long term sequalae (Long COVID)
which include neurological and behavioral effects in thousands of patients, but the etiology …

[HTML][HTML] Non-invasive vagal nerve stimulation decreases brain activity during trauma scripts

MT Wittbrodt, NZ Gurel, JA Nye, S Ladd, MMH Shandhi… - Brain stimulation, 2020 - Elsevier
Background Traumatic stress can have lasting effects on neurobiology and result in
psychiatric conditions such as posttraumatic stress disorder (PTSD). We hypothesize that …

Transcutaneous vagal nerve stimulation blocks stress-induced activation of interleukin-6 and interferon-γ in posttraumatic stress disorder: a double-blind, randomized …

JD Bremner, NZ Gurel, Y Jiao, MT Wittbrodt… - Brain, Behavior, & …, 2020 - Elsevier
Posttraumatic stress disorder (PTSD) is a highly disabling condition associated with
alterations in multiple neurobiological systems, including increases in inflammatory function …

Transcutaneous cervical vagal nerve stimulation reduces sympathetic responses to stress in posttraumatic stress disorder: A double-blind, randomized, sham …

NZ Gurel, MT Wittbrodt, H Jung, MMH Shandhi… - Neurobiology of …, 2020 - Elsevier
Objective Exacerbated autonomic responses to acute stress are prevalent in posttraumatic
stress disorder (PTSD). The purpose of this study was to assess the effects of …

Transcutaneous cervical vagal nerve stimulation in patients with posttraumatic stress disorder (PTSD): a pilot study of effects on PTSD symptoms and interleukin-6 …

JD Bremner, MT Wittbrodt, NZ Gurel… - Journal of affective …, 2021 - Elsevier
Background Posttraumatic stress disorder (PTSD) is a highly disabling condition associated
with alterations in multiple neurobiological systems, including increases in inflammatory and …

Automatic detection of target engagement in transcutaneous cervical vagal nerve stimulation for traumatic stress triggers

NZ Gurel, MT Wittbrodt, H Jung, SL Ladd… - IEEE journal of …, 2020 - ieeexplore.ieee.org
Transcutaneous cervical vagal nerve stimulation (tcVNS) devices are attractive alternatives
to surgical implants, and can be applied for a number of conditions in ambulatory settings …

Synthetic seismocardiogram generation using a transformer-based neural network

M Nikbakht, AH Gazi, J Zia, S An, DJ Lin… - Journal of the …, 2023 - academic.oup.com
Objective To design and validate a novel deep generative model for seismocardiogram
(SCG) dataset augmentation. SCG is a noninvasively acquired cardiomechanical signal …

[HTML][HTML] Digital cardiovascular biomarker responses to transcutaneous cervical vagus nerve stimulation: state-space modeling, prediction, and simulation

AH Gazi, NZ Gurel, KLS Richardson… - JMIR mHealth and …, 2020 - mhealth.jmir.org
Background: Transcutaneous cervical vagus nerve stimulation (tcVNS) is a promising
alternative to implantable stimulation of the vagus nerve. With demonstrated potential in …

Nonimprovement in chronic fatigue syndrome: Relation to activity patterns, uplifts and hassles, and autonomic dysfunction

F Friedberg, JL Adamowicz, P Bruckenthal… - Psychosomatic …, 2022 - journals.lww.com
Objective To test a model of nonimprovement in chronic fatigue syndrome (CFS) using self-
report activity patterns (eg,“push-crash”), uplifts and hassles, and a biological measure of …