[HTML][HTML] Glucagon-like peptide 1 (GLP-1)
TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …
Biology of incretins: GLP-1 and GIP
LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier
This review focuses on the mechanisms regulating the synthesis, secretion, biological
actions, and therapeutic relevance of the incretin peptides glucose-dependent insulinotropic …
actions, and therapeutic relevance of the incretin peptides glucose-dependent insulinotropic …
The physiology of glucagon-like peptide 1
JJ Holst - Physiological reviews, 2007 - journals.physiology.org
Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in the
intestinal epithelial endocrine L-cells by differential processing of proglucagon, the gene …
intestinal epithelial endocrine L-cells by differential processing of proglucagon, the gene …
The enteric network: interactions between the immune and nervous systems of the gut
BB Yoo, SK Mazmanian - Immunity, 2017 - cell.com
Interactions between the nervous and immune systems enable the gut to respond to the
variety of dietary products that it absorbs, the broad spectrum of pathogens that it …
variety of dietary products that it absorbs, the broad spectrum of pathogens that it …
Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?
The incretin hormones gastric inhibitory polypeptide and especially glucagon-like peptide
(GLP) have an important physiological function in augmenting postprandial insulin …
(GLP) have an important physiological function in augmenting postprandial insulin …
Sotagliflozin, the first dual SGLT inhibitor: current outlook and perspectives
CMA Cefalo, F Cinti, S Moffa, F Impronta… - Cardiovascular …, 2019 - Springer
Sotagliflozin is a dual sodium–glucose co-transporter-2 and 1 (SGLT2/1) inhibitor for the
treatment of both type 1 (T1D) and type 2 diabetes (T2D). Sotagliflozin inhibits renal sodium …
treatment of both type 1 (T1D) and type 2 diabetes (T2D). Sotagliflozin inhibits renal sodium …
GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell
LM Lauffer, R Iakoubov, PL Brubaker - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Intestinal L-cells secrete the incretin glucagon-like peptide-1 (GLP-1) in
response to ingestion of nutrients, especially long-chain fatty acids. The Gαs-coupled …
response to ingestion of nutrients, especially long-chain fatty acids. The Gαs-coupled …
Glucagon‐like peptide 1 (GLP‐1) in biology and pathology
JJ Meier, MA Nauck - Diabetes/metabolism research and …, 2005 - Wiley Online Library
Post‐translational proteolytic processing of the preproglucagon gene in the gut results in the
formation of glucagon‐like peptide 1 (GLP‐1). Owing to its glucose‐dependent …
formation of glucagon‐like peptide 1 (GLP‐1). Owing to its glucose‐dependent …
The emerging role of polyphenols in the management of type 2 diabetes
Type 2 diabetes (T2D) is a fast-increasing health problem globally, and it results from insulin
resistance and pancreatic β-cell dysfunction. The gastrointestinal (GI) tract is recognized as …
resistance and pancreatic β-cell dysfunction. The gastrointestinal (GI) tract is recognized as …
Colocalization of the α-subunit of gustducin with PYY and GLP-1 in L cells of human colon
N Rozengurt, SV Wu, MC Chen… - American journal …, 2006 - journals.physiology.org
In view of the importance of molecular sensing in the function of the gastrointestinal (GI)
tract, we assessed whether signal transduction proteins that mediate taste signaling are …
tract, we assessed whether signal transduction proteins that mediate taste signaling are …