Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …

Background Older people taking multiple medications represent a large and growing
proportion of the population. Managing multiple medications can be challenging, and this is …

Background Individuals with dementia or mild cognitive impairment frequently have multiple
chronic conditions (defined as≥ 2 chronic medical conditions) and take multiple …

Background There is a rising prevalence of multimorbidity, particularly in older patients, and
a need for evidence-based medicines management interventions for this population. The …

Interpreting results from deprescribing interventions to generate actionable evidence is
challenging owing to inconsistent and heterogeneous outcome definitions between studies …

BACKGROUND Tackling problematic polypharmacy requires tailoring the use of medicines
to individual needs and circumstances. This may involve stop** medicines (deprescribing) …

The correct management of patients with multimorbidity remains one of the main challenges
for healthcare systems worldwide. In this study, we analyze the existence of multimorbidity …

Abstract Background and Objectives To investigate the reproducibility and validity of latent
class analysis (LCA) and hierarchical cluster analysis (HCA), multiple correspondence …

Background Potentially inappropriate medications (PIM) for the older adults are those with
an unfavorable risk-benefit ratio when more effective and safe therapeutic alternatives are …

Objective Limited evidence suggests integration of pharmacists into the general practice
team could improve medicines management for patients, particularly those with …