The liver as an endocrine organ—linking NAFLD and insulin resistance
MJ Watt, PM Miotto, W De Nardo… - Endocrine …, 2019 - academic.oup.com
The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …
Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance
RCR Meex, MJ Watt - Nature Reviews Endocrinology, 2017 - nature.com
Hepatic steatosis is an underlying feature of nonalcoholic fatty liver disease (NAFLD), which
is the most common form of liver disease and is present in up to∼ 70% of individuals who …
is the most common form of liver disease and is present in up to∼ 70% of individuals who …
Pyruvate dehydrogenase kinases (PDKs): an overview toward clinical applications
X Wang, X Shen, Y Yan, H Li - Bioscience Reports, 2021 - portlandpress.com
Pyruvate dehydrogenase kinase (PDK) can regulate the catalytic activity of pyruvate
decarboxylation oxidation via the mitochondrial pyruvate dehydrogenase complex, and it …
decarboxylation oxidation via the mitochondrial pyruvate dehydrogenase complex, and it …
[HTML][HTML] Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance
Objective The peptide hormone adropin regulates fuel selection preferences in skeletal
muscle under fed and fasted conditions. Here, we investigated whether adropin treatment …
muscle under fed and fasted conditions. Here, we investigated whether adropin treatment …
Adropin as a fat-burning hormone with multiple functions—Review of a decade of research
M Jasaszwili, M Billert, MZ Strowski, KW Nowak… - Molecules, 2020 - mdpi.com
Adropin is a unique hormone encoded by the energy homeostasis-associated (Enho) gene.
Adropin is produced in the liver and brain, and also in peripheral tissues such as in the heart …
Adropin is produced in the liver and brain, and also in peripheral tissues such as in the heart …
Hormonal alterations in PCOS and its influence on bone metabolism
A Krishnan, S Muthusami - Journal of Endocrinology, 2017 - joe.bioscientifica.com
According to the World Health Organization (WHO) polycystic ovary syndrome (PCOS)
occurs in 4–8% of women worldwide. The prevalence of PCOS in Indian adolescents is …
occurs in 4–8% of women worldwide. The prevalence of PCOS in Indian adolescents is …
[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …
[HTML][HTML] Adropin protects against liver injury in nonalcoholic steatohepatitis via the Nrf2 mediated antioxidant capacity
X Chen, H Xue, W Fang, K Chen, S Chen, W Yang… - Redox biology, 2019 - Elsevier
Adropin, a secretory signal peptide, has shown beneficial effects on improving glucose
homeostasis and dyslipidemia. However, whether this peptide affects nonalcoholic …
homeostasis and dyslipidemia. However, whether this peptide affects nonalcoholic …
Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF) 1 and HNF4 families: functional and pathological …
GU Ryffel - Journal of molecular endocrinology, 2001 - jme.bioscientifica.com
The subcellular distribution of steroidogenic enzymes has so far been studied mostly in
classical endocrine glands and in the placenta. In the peripheral intracrine organs which …
classical endocrine glands and in the placenta. In the peripheral intracrine organs which …
[HTML][HTML] Organ-organ communication: The liver's perspective
Communication between organs participates in most physiological and pathological events.
Owing to the importance of precise coordination among the liver and virtually all organs in …
Owing to the importance of precise coordination among the liver and virtually all organs in …