[HTML][HTML] Leishmania infections: Molecular targets and diagnosis

M Akhoundi, T Downing, J Votýpka, K Kuhls… - Molecular aspects of …, 2017 - Elsevier
Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …

Molecular diagnosis of visceral leishmaniasis

S Sundar, OP Singh - Molecular diagnosis & therapy, 2018 - Springer
Visceral leishmaniasis (VL), a deadly parasitic disease, is a major public health concern
globally. Countries affected by VL have signed the London Declaration on Neglected …

Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

I Gow, NC Smith, D Stark, J Ellis - Parasites & Vectors, 2022 - Springer
Leishmania infections span a range of clinical syndromes and impact humans from many
geographic foci, but primarily the world's poorest regions. Transmitted by the bite of a female …

Molecular tools for diagnosis of visceral leishmaniasis: systematic review and meta-analysis of diagnostic test accuracy

CM De Ruiter, C Van Der Veer… - Journal of clinical …, 2014 - Am Soc Microbiol
Molecular methods have been proposed as highly sensitive tools for the detection of
Leishmania parasites in visceral leishmaniasis (VL) patients. Here, we evaluate the …

Diagnosis of visceral leishmaniasis: developments over the last decade

G Srividya, A Kulshrestha, R Singh, P Salotra - Parasitology research, 2012 - Springer
Diagnostic parameters for visceral leishmaniasis (VL), a potentially fatal parasitic disease
caused by Leishmania donovani, have been redefined in the last decade with the …

Immune regulation during chronic visceral leishmaniasis

RJ Faleiro, R Kumar, LM Hafner… - PLoS neglected tropical …, 2014 - journals.plos.org
Visceral leishmaniasis is a chronic parasitic disease associated with severe immune
dysfunction. Treatment options are limited to relatively toxic drugs, and there is no vaccine …

Comparative study of rK39 Leishmania antigen for serodiagnosis of visceral leishmaniasis: systematic review with meta-analysis

Z Maia, M Lírio, S Mistro, CMC Mendes… - PLoS neglected …, 2012 - journals.plos.org
Background The rK39 recombinant protein is derived from a specific antigen produced by
the Leishmania donovani complex, and has been used in the last two decades for the …

Extracellular Onchocerca-derived small RNAs in host nodules and blood

JF Quintana, BL Makepeace, SA Babayan, A Ivens… - Parasites & vectors, 2015 - Springer
Background microRNAs (miRNAs), a class of short, non-coding RNA can be found in a
highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by …

Nanodiagnostics in leishmaniasis: A new frontiers for early elimination

MR Gedda, P Madhukar, A Shukla… - Wiley …, 2021 - Wiley Online Library
Visceral leishmaniasis (VL) is still a major public health concern in develo** countries
having the highest outbreak and mortality potential. While the treatment of VL has greatly …

Nano-structured nickel oxide based DNA biosensor for detection of visceral leishmaniasis (Kala-azar)

S Mohan, P Srivastava, SN Maheshwari, S Sundar… - Analyst, 2011 - pubs.rsc.org
Sol–gel synthesized nickel oxide (NiO) film deposited onto indium tin oxide (ITO) coated
glass plate has been utilized for the development of sensitive and stable DNA biosensor and …