The persistent dilemma of microbial keratitis: Global burden, diagnosis, and antimicrobial resistance
Microbial keratitis is a potentially blinding condition that must be treated emergently to
preserve vision. Although long recognized as a significant cause of corneal blindness, our …
preserve vision. Although long recognized as a significant cause of corneal blindness, our …
[HTML][HTML] Application of next generation sequencing in laboratory medicine
The rapid development of next-generation sequencing (NGS) technology, including
advances in sequencing chemistry, sequencing technologies, bioinformatics, and data …
advances in sequencing chemistry, sequencing technologies, bioinformatics, and data …
Major data analysis errors invalidate cancer microbiome findings
We re-analyzed the data from a recent large-scale study that reported strong correlations
between DNA signatures of microbial organisms and 33 different cancer types and that …
between DNA signatures of microbial organisms and 33 different cancer types and that …
Metagenome analysis using the Kraken software suite
Metagenomic experiments expose the wide range of microscopic organisms in any
microbial environment through high-throughput DNA sequencing. The computational …
microbial environment through high-throughput DNA sequencing. The computational …
Fungal keratitis: An overview of clinical and laboratory aspects
Mycotic keratitis or keratomycosis is a fungal infection with global distribution. The dominant
aetiology of this disease varies based on geographical origin, socioeconomic status, and …
aetiology of this disease varies based on geographical origin, socioeconomic status, and …
[HTML][HTML] The global epidemiology and clinical diagnosis of Acanthamoeba keratitis
Y Zhang, X Xu, Z Wei, K Cao, Z Zhang… - Journal of Infection and …, 2023 - Elsevier
Acanthamoeba keratitis is a rare parasitic infection of the cornea that can lead to permanent
blindness if not diagnosed and treated promptly. We collected data on the incidences of …
blindness if not diagnosed and treated promptly. We collected data on the incidences of …
Bacterial keratitis: identifying the areas of clinical uncertainty
S Tuft, TF Somerville, JPO Li, T Neal, S De… - Progress in retinal and …, 2022 - Elsevier
Bacterial keratitis is a common corneal infection that is treated with topical antimicrobials. By
the time of presentation there may already be severe visual loss from corneal ulceration and …
the time of presentation there may already be severe visual loss from corneal ulceration and …
[HTML][HTML] Diagnostic armamentarium of infectious keratitis: A comprehensive review
Infectious keratitis (IK) represents the leading cause of corneal blindness worldwide,
particularly in develo** countries. A good outcome of IK is contingent upon timely and …
particularly in develo** countries. A good outcome of IK is contingent upon timely and …
Next-generation sequencing in clinical microbiology: are we there yet?
SL Mitchell, PJ Simner - Clinics in laboratory medicine, 2019 - labmed.theclinics.com
Next-generation sequencing (NGS) is a method that allows for high-throughput, massively
parallel sequencing of thousands to billions of DNA fragments independently and …
parallel sequencing of thousands to billions of DNA fragments independently and …
The role of fungi in fungal keratitis
Fungal keratitis (FK) accounts for approximately half of the microbial keratitis encountered in
low middle income countries (LMICs) and predominantly affect the working rural-poor. FK …
low middle income countries (LMICs) and predominantly affect the working rural-poor. FK …