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Deuterium‐and tritium‐labelled compounds: applications in the life sciences
J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …
Metabolomics for plant stress response
Stress in plants could be defined as any change in growth condition (s) that disrupts
metabolic homeostasis and requires an adjustment of metabolic pathways in a process that …
metabolic homeostasis and requires an adjustment of metabolic pathways in a process that …
Advances in structure elucidation of small molecules using mass spectrometry
The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …
role in modern life sciences and bioanalytical approaches. This review covers different soft …
Applications of NMR spectroscopy to systems biochemistry
TWM Fan, AN Lane - Progress in nuclear magnetic resonance spectroscopy, 2016 - Elsevier
The past decades of advancements in NMR have made it a very powerful tool for metabolic
research. Despite its limitations in sensitivity relative to mass spectrometric techniques, NMR …
research. Despite its limitations in sensitivity relative to mass spectrometric techniques, NMR …
Elemental formula annotation of polar and lipophilic metabolites using 13C, 15N and 34S isotope labelling, in combination with high‐resolution mass spectrometry
P Giavalisco, Y Li, A Matthes, A Eckhardt… - The Plant …, 2011 - Wiley Online Library
The unbiased and comprehensive analysis of metabolites in any organism presents a major
challenge if proper peak annotation and unambiguous assignment of the biological origin of …
challenge if proper peak annotation and unambiguous assignment of the biological origin of …
Differential 12C-/13C-Isotope Dansylation Labeling and Fast Liquid Chromatography/Mass Spectrometry for Absolute and Relative Quantification of the Metabolome
We report a new quantitative metabolome profiling technique based on differential 12C-/13C-
isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and …
isotope dansylation labeling of metabolites, fast liquid chromatography (LC) separation and …
Stable isotope-labeling studies in metabolomics: new insights into structure and dynamics of metabolic networks
The rapid emergence of metabolomics has enabled system-wide measurements of
metabolites in various organisms. However, advances in the mechanistic understanding of …
metabolites in various organisms. However, advances in the mechanistic understanding of …
Avoiding misannotation of in-source fragmentation products as cellular metabolites in liquid chromatography–mass spectrometry-based metabolomics
Liquid chromatography–mass spectrometry (LC-MS) technology allows for rapid quantitation
of cellular metabolites, with metabolites identified by mass spectrometry and …
of cellular metabolites, with metabolites identified by mass spectrometry and …
Metabolomic technologies and their application to the study of plants and plant–host interactions
Metabolomics is perhaps the ultimate level of post‐genomic analysis as it can reveal
changes in metabolite fluxes that are controlled by only minor changes within gene …
changes in metabolite fluxes that are controlled by only minor changes within gene …
Ultra performance liquid chromatography and high resolution mass spectrometry for the analysis of plant lipids
J Hummel, S Segu, Y Li, S Irgang, J Jueppner… - Frontiers in plant …, 2011 - frontiersin.org
Holistic analysis of lipids is becoming increasingly popular in the life sciences. Recently,
several interesting, mass spectrometry-based studies have been conducted, especially in …
several interesting, mass spectrometry-based studies have been conducted, especially in …