Inferring human phenotypes using ancient DNA: from molecules to populations

M Ferrando-Bernal, CM Brand, JA Capra - Current Opinion in Genetics & …, 2025 - Elsevier
The increasing availability of ancient DNA (aDNA) from human groups across space and
time has yielded deep insights into the movements of our species. However, given the …

Archaic hominin admixture and its consequences for modern humans

D Tagore, JM Akey - Current Opinion in Genetics & Development, 2025 - Elsevier
As anatomically modern humans dispersed out of Africa, they encountered and mated with
now extinct hominins, including Neanderthals and Denisovans. It is now well established …

On the issue of adaptive fitness of chronotypes in high latitudes

M Borisenkov, D Gubin, K Sergey - Biological Rhythm Research, 2024 - Taylor & Francis
Human adaptation to environment is complex trait. Given close connection of circadian
rhythms with environment, it is quite evident to suppose that adaptation played a significant …

Validation and TaqMan Conversion of a Molecular Chronotype Assessment Approach

A Biscontin, A Russo, D Marnetto… - Journal of …, 2024 - journals.sagepub.com
The present study aimed to develop a TaqMan genoty** card for molecular chronotype
assessment based on a predictive panel of 35 previously identified genetic variants. A …

[HTML][HTML] Human dispersal into East Eurasia: ancient genome insights and the need for research on physiological adaptations

S Abood, H Oota - Journal of Physiological …, 2025 - jphysiolanthropol.biomedcentral …
Humans have long pondered their genesis. The answer to the great question of where
Homo sapiens come from has evolved in conjunction with biotechnologies that have …

Extreme chronotype, regardless of misalignment, links to cardiovascular disease risks

T Partonen - Sleep, 2023 - academic.oup.com
Social schedules in addition to the biological rhythms guide behaviors. Sleep is among
these guided behaviors, because the sleep–wakefulness cycle is a product of the …

Exploring adaptive introgression in modern human circadian rhythm genes

C Kendall, A Nooranikhojasteh, G Debortoli… - bioRxiv, 2024 - biorxiv.org
Interbreeding between modern humans and archaic hominins, including Neanderthals and
Denisovans, occurred as modern humans migrated outside of Africa. Here, we report on …

Insights into Human Evolution through Paleogenomics

HA Ranganath - Resonance, 2024 - Springer
The article narrates the success story of the investigations of S Pääbo and his team. It
centres around the analysis of paleogenomes of extinct hominins, our immediate ancestors …

[PDF][PDF] Quantifying Effects of Partial Genetic Backgrounds to Decode Genetic Drivers of Clinical Phenotypes

R Pauly - 2024 - open.clemson.edu
Understanding partial genetic backgrounds illuminates the genetic architecture of complex
traits and diseases, revealing how diverse genetic backgrounds contribute to phenotypic …

[PDF][PDF] ISTANBUL TECHNICAL UNIVERSITY★ GRADUATE SCHOOL

B Şensoy - 2024 - polen.itu.edu.tr
Interspecific gene flow plays a critical role in evolutionary biology. It shapes population
genetic composition and speciation dynamics, as well as influencing species' ability to …