Monocyte chemoattractant protein-1 (MCP-1/CCL2) is renowned for its ability to drive the
chemotaxis of myeloid and lymphoid cells. It orchestrates the migration of these cell types …

Metastasis has intrigued researchers for more than 100 years. Despite the development of
technologies and therapeutic strategies, metastasis is still the major cause of cancer-related …

A key aspect of cancer metastases is the tendency for specific cancer cells to home to
defined subsets of secondary organs. Despite these known tendencies, the underlying …

Cell-cell interactions and cell adhesion are key mediators of cancer progression and
facilitate hallmarks of cancer including immune evasion and metastatic dissemination. Many …

Abstract Background Wumei Wan (WMW) has been used to address digestive disorder for
centuries in traditional Chinese medicine. Previous studies have demonstrated its anti-colitis …

Zebrafish are teleosts (bony fish) that share with mammals a common ancestor belonging to
the phylum Osteichthyes, from which their endoskeletal systems have been inherited …

The tumor microenvironment (TME) plays key roles in promoting disease progression in the
aggressive triple-negative subtype of breast cancer (TNBC; Basal/Basal-like). Here, we took …

Metastasis still represents the primary cause of cancer morbidity and mortality worldwide.
Chemokine signalling contributes to the overall process of cancer growth and metastasis …

The anti-tumor activities of some members of the chemokine family are often overcome by
the functions of many chemokines that are strongly and causatively linked with increased …

Short-chain fatty acids (SCFAs) derived from the fermentation of carbohydrates by gut
microbiota play a crucial role in regulating host physiology. Among them, acetate …