Role of polyphenols on gut microbiota and the ubiquitin-proteasome system in neurodegenerative diseases
H Nargeh, F Aliabadi, M Ajami… - Journal of Agricultural …, 2021 - ACS Publications
Today, neurodegenerative diseases have become a remarkable public health challenge
due to their direct relation with aging. Accordingly, understanding the molecular and cellular …
due to their direct relation with aging. Accordingly, understanding the molecular and cellular …
Increased transport of acetyl‐CoA into the endoplasmic reticulum causes a progeria‐like phenotype
The membrane transporter AT‐1/SLC33A1 translocates cytosolic acetyl‐CoA into the lumen
of the endoplasmic reticulum (ER), participating in quality control mechanisms within the …
of the endoplasmic reticulum (ER), participating in quality control mechanisms within the …
Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology
N ε-lysine acetylation within the lumen of the endoplasmic reticulum is a recently
characterized protein quality control system that positively selects properly folded …
characterized protein quality control system that positively selects properly folded …
Therapeutic effect of Rho kinase inhibitor FSD‑C10 in a mouse model of Alzheimer's disease
QF Gu, JZ Yu, H Wu, YH Li, CY Liu… - Experimental and …, 2018 - spandidos-publications.com
Fasudil, a Rho kinase (ROCK) inhibitor, effectively inhibits disease severity in a mouse
model of Alzheimer's disease (AD). However, given its significant limitations, including a …
model of Alzheimer's disease (AD). However, given its significant limitations, including a …
SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype
Endoplasmic reticulum-based N ɛ-lysine acetylation serves as an important protein quality
control system for the secretory pathway. Dysfunctional endoplasmic reticulum-based …
control system for the secretory pathway. Dysfunctional endoplasmic reticulum-based …
Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism
Nε-lysine acetylation in the ER lumen is a recently discovered quality control mechanism
that ensures proteostasis within the secretory pathway. The acetyltransferase reaction is …
that ensures proteostasis within the secretory pathway. The acetyltransferase reaction is …
The endoplasmic reticulum acetyltransferases ATase1/NAT8B and ATase2/NAT8 are differentially regulated to adjust engagement of the secretory pathway
Nε‐lysine acetylation of nascent glycoproteins within the endoplasmic reticulum (ER) lumen
regulates the efficiency of the secretory pathway. The ER acetylation machinery consists of …
regulates the efficiency of the secretory pathway. The ER acetylation machinery consists of …
[PDF][PDF] BRAIN COMMUNICATIONS AIN COMMUNICATIONS
SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity
and an autistic-like phenotype Page 1 SLC13A5/sodium-citrate co-transporter overexpression …
and an autistic-like phenotype Page 1 SLC13A5/sodium-citrate co-transporter overexpression …
[KIRJA][B] Endoplasmic Reticulum-Based Nε-Lysine Acetylation in the Neuron: Regulator of Proteostasis and Intracellular Crosstalk
MJ Rigby - 2021 - search.proquest.com
N ε-lysine acetylation is the covalent addition of an acetyl group on the lysine side chain
epsilon-primary amine that is able to impact protein structure and function. In 2007, N ε …
epsilon-primary amine that is able to impact protein structure and function. In 2007, N ε …
The Role of Fatty Acids on Endoplasmic Reticulum Proteostasis in Non-Alcoholic Fatty Liver Disease
AL Estrada - 2017 - search.proquest.com
Non-alcoholic fatty liver disease (NAFLD) is currently a significant health concern in both
adults and children. NAFLD is a disease characterized by accumulation of fat in the liver …
adults and children. NAFLD is a disease characterized by accumulation of fat in the liver …