Soft contact lenses as drug delivery systems: a review

I Rykowska, I Nowak, R Nowak - Molecules, 2021 - mdpi.com
This review describes the role of contact lenses as an innovative drug delivery system in
treating eye diseases. Current ophthalmic drug delivery systems are inadequate, particularly …

Cyclodextrin-containing hydrogels: A review of preparation method, drug delivery, and degradation behavior

J Liu, B Tian, Y Liu, JB Wan - International Journal of Molecular Sciences, 2021 - mdpi.com
Hydrogels possess porous structures, which are widely applied in the field of materials and
biomedicine. As a natural oligosaccharide, cyclodextrin (CD) has shown remarkable …

[HTML][HTML] Inkjet drug printing onto contact lenses: deposition optimisation and non-destructive dose verification

TD Pollard, I Seoane-Viano, JJ Ong… - International Journal of …, 2023 - Elsevier
Inkjet printing has the potential to advance the treatment of eye diseases by printing drugs
on demand onto contact lenses for localised delivery and personalised dosing, while near …

Therapeutic applications of contact lens-based drug delivery systems in ophthalmic diseases

L Zhao, J Song, Y Du, C Ren, B Guo, H Bi - Drug Delivery, 2023 - Taylor & Francis
Traditional ophthalmic drugs, such as eye drops, gels and ointments, are accompanied by
many problems, including low bioavailability and potential drug side effects. Innovative …

Technological evolution of cyclodextrins in the pharmaceutical field

J Rincón-López, YC Almanza-Arjona… - Journal of Drug Delivery …, 2021 - Elsevier
We herein disclose how global cyclodextrin-based pharmaceutical technologies have
evolved since the early 80s through a 1998 patents dataset retrieved from Derwent …

Drug-free contact lens based on quaternized chitosan and tannic acid for bacterial keratitis therapy and corneal repair

Z Jiao, Q Huo, X Lin, X Chu, Z Deng, H Guo… - Carbohydrate …, 2022 - Elsevier
Bacterial keratitis (BK) and related inflammatory diseases causes irreversible damage to the
corneal tissue. In this study, a novel polyacrylamide semi-interpenetrating network hydrogel …

[HTML][HTML] Contact lens as an emerging platform for ophthalmic drug delivery: A systematic review

H Yang, M Zhao, D **ng, J Zhang, T Fang… - Asian Journal of …, 2023 - Elsevier
The number of people with eye diseases has increased with the use of electronics.
However, the bioavailability of eye drops remains low owing to the presence of the ocular …

Therapeutic ophthalmic lenses: a review

N Toffoletto, B Saramago, AP Serro - Pharmaceutics, 2020 - mdpi.com
An increasing incidence of eye diseases has been registered in the last decades in
developed countries due to the ageing of population, changes in lifestyle, environmental …

Contact lenses as drug delivery system for glaucoma: a review

A Peral, A Martinez-Aguila, C Pastrana, F Huete-Toral… - Applied sciences, 2020 - mdpi.com
Glaucoma is an optical neuropathy associated to a progressive degeneration of retinal
ganglion cells with visual field loss and is the main cause of irreversible blindness in the …

Alternative therapeutic interventions: antimicrobial peptides and small molecules to treat microbial keratitis

PK Jadi, P Sharma, B Bhogapurapu, S Roy - Frontiers in Chemistry, 2021 - frontiersin.org
Microbial keratitis is a leading cause of blindness worldwide and results in unilateral vision
loss in an estimated 2 million people per year. Bacteria and fungus are two main etiological …