Regional aerosol deposition in the human airways: The SimInhale benchmark case and a critical assessment of in silico methods

P Koullapis, SC Kassinos, J Muela… - European Journal of …, 2018 - Elsevier
Regional deposition effects are important in the pulmonary delivery of drugs intended for the
topical treatment of respiratory ailments. They also play a critical role in the systemic delivery …

[BUKU][B] Multiphase flow handbook

E Michaelides, CT Crowe, JD Schwarzkopf - 2016 - books.google.com
The Multiphase Flow Handbook, Second Edition is a thoroughly updated and reorganized
revision of the late Clayton Crowe's work, and provides a detailed look at the basic concepts …

From indoor exposure to inhaled particle deposition: A multiphase journey of inhaled particles

K Inthavong - Experimental and computational multiphase flow, 2020 - Springer
Indoor air quality and its effect on respiratory health are reliant on understanding the level of
inhalation exposure, particle inhalability, and particle deposition in the respiratory airway. In …

Investigating the effect of air conditioning on the distribution and transmission of COVID-19 virus particles

M Ahmadzadeh, E Farokhi, M Shams - Journal of Cleaner Production, 2021 - Elsevier
The effect of indoor airflow has been confirmed on the diffusion and transmission of droplets
generated when talking or sneezing by a person with a viral respiratory infection such as …

Prediction of respiratory droplets evolution for safer academic facilities planning amid COVID-19 and future pandemics: A numerical approach

JJ Quinones, A Doosttalab, S Sokolowski… - Journal of Building …, 2022 - Elsevier
Airborne dispersion of the novel SARS-CoV-2 through the droplets produced during
expiratory activities is one of the main transmission mechanisms of this virus from one …

[HTML][HTML] Development of an effective two-equation turbulence modeling approach for simulating aerosol deposition across a range of turbulence levels

H Jubaer, M Thomas, D Farkas, AV Kolanjiyil… - Journal of aerosol …, 2024 - Elsevier
Pharmaceutical aerosol systems present a significant challenge to computational fluid
dynamics (CFD) modeling based on the need to capture multiple levels of turbulence …

Numerical analysis of stochastic dispersion of micro-particles in turbulent flows in a realistic model of human nasal/upper airway

E Ghahramani, O Abouali, H Emdad… - Journal of aerosol science, 2014 - Elsevier
Turbulent flow field and particle deposition in a realistic model of human upper airway
system including: nasal cavity, nasopharynx, oropharynx, larynx and trachea were analyzed …

Characterization of aerosol Stokes number in 90° bends and idealized extrathoracic airways

L Nicolaou, TA Zaki - Journal of Aerosol Science, 2016 - Elsevier
Prediction of aerosol deposition in the respiratory system is important for improving the
efficiency of inhaled drug delivery and for assessing the toxicity of airborne pollutants …

Numerical investigation of turbulent airflow and microparticle deposition in a realistic model of human upper airway using LES

E Ghahramani, O Abouali, H Emdad, G Ahmadi - Computers & Fluids, 2017 - Elsevier
Abstract The Large Eddy Simulation (LES) technique was used to study the turbulent airflow
field in a realistic model of human upper airways from nostril to the end of trachea. The …

Direct numerical simulations of flow in realistic mouth–throat geometries

L Nicolaou, TA Zaki - Journal of aerosol science, 2013 - Elsevier
The flow in a set of four realistic mouth–throat geometries at a flow rate of 30L/min is studied
in order to determine the effect of intrasubject and intersubject variations on the mean flow …