Pulmonary drug delivery by powder aerosols

MY Yang, JGY Chan, HK Chan - Journal of Controlled Release, 2014 - Elsevier
The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …

In silico models of aerosol delivery to the respiratory tract—Development and applications

PW Longest, LT Holbrook - Advanced drug delivery reviews, 2012 - Elsevier
This review discusses the application of computational models to simulate the transport and
deposition of inhaled pharmaceutical aerosols from the site of particle or droplet formation to …

[KNIHA][B] Polymer Surface Modification: Relevance to Adhesion, Volume 3

KL Mittal - 2004 - books.google.com
This book documents the proceedings of the Fourth International Symposium on Polymer
Surface Modification: Relevance to Adhesion. This volume and its predecessors containing …

The impact of electrostatic charge in pharmaceutical powders with specific focus on inhalation-powders

S Karner, NA Urbanetz - Journal of Aerosol Science, 2011 - Elsevier
The aim of this work is to give an overview about the literature available on the topic of
electrostatic charge in pharmaceutical powders. The main focus is on powders used in dry …

Triboelectrification of pharmaceutical powders by particle impact

H Watanabe, M Ghadiri, T Matsuyama, YL Ding… - International journal of …, 2007 - Elsevier
Pharmaceutical powders are very prone to electrostatic charging by colliding and sliding
contacts with walls and other particles. In pharmaceutical formulation processes, particle …

Twenty-first century research needs in electrostatic processes applied to industry and medicine

MK Mazumder, RA Sims, AS Biris, PK Srirama… - Chemical Engineering …, 2006 - Elsevier
From the early 20th century Nobel Prize winning (1923) experiments with charged oil
droplets, resulting in the discovery of the elementary electronic charge by Robert Millikan, to …

A review of factors affecting electrostatic charging of pharmaceuticals and adhesive mixtures for inhalation

W Kaialy - International journal of pharmaceutics, 2016 - Elsevier
Pharmaceutical powders are typically insulators consisting of relatively small particles and
thus they usually exhibit significant electrostatic charging behaviours. In the inhalation field …

Dry powder aerosol delivery systems: current and future research directions

HK Chan - Journal of aerosol medicine, 2006 - liebertpub.com
Development of dry powder aerosol delivery system involves powder production,
formulation, dispersion, delivery, and deposition of the powder aerosol in the airways …

Dry powder aerosol drug delivery—Opportunities for colloid and surface scientists

HK Chan - Colloids and Surfaces A: Physicochemical and …, 2006 - Elsevier
Development of dry powder aerosol drug delivery system includes powder production,
formulation, dispersion, and delivery of the powder aerosol to the lung. Conventional …

Electrostatic charge characterization of pharmaceutical aerosols using electrical low-pressure impaction (ELPI)

W Glover, HK Chan - Journal of aerosol science, 2004 - Elsevier
A novel method for characterizing the electrostatic charge in pharmaceutical aerosols was
developed. Electrical low-pressure impaction (ELPI) was modified and optimized to allow …