Image-guided ultrasound phased arrays are a disruptive technology for non-invasive therapy

K Hynynen, RM Jones - Physics in Medicine & Biology, 2016 - iopscience.iop.org
Focused ultrasound offers a non-invasive way of depositing acoustic energy deep into the
body, which can be harnessed for a broad spectrum of therapeutic purposes, including …

A review of numerical and experimental compensation techniques for skull-induced phase aberrations in transcranial focused ultrasound

A Kyriakou, E Neufeld, B Werner… - International journal …, 2014 - Taylor & Francis
The development of phased array transducers and their integration with magnetic
resonance (MR) guidance and thermal monitoring has established transcranial MR-guided …

3D-printed adaptive acoustic lens as a disruptive technology for transcranial ultrasound therapy using single-element transducers

G Maimbourg, A Houdouin, T Deffieux… - Physics in Medicine …, 2018 - iopscience.iop.org
The development of multi-element arrays for better control of the shape of ultrasonic beams
has opened the way for focusing through highly aberrating media, such as the human skull …

[HTML][HTML] Low-intensity focused ultrasound to the posterior insula reduces temporal summation of pain

A In, A Strohman, B Payne, W Legon - Brain stimulation, 2024 - Elsevier
Background The insula and dorsal anterior cingulate cortex (dACC) are core brain regions
involved in pain processing and central sensitization, a shared mechanism across various …

A 200–1380-kHz Quadrifrequency Focused Ultrasound Transducer for Neurostimulation in Rodents and Primates: Transcranial In Vitro Calibration and Numerical …

C Constans, T Deffieux, P Pouget… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Low intensity transcranial focused ultrasound has been demonstrated to produce
neuromodulation in both animals and humans. Primarily for technical reasons, frequency is …

[HTML][HTML] Examination of the interaction of parameters for low-intensity focused ultrasound of the human motor cortex

A Ennasr, G Isaac, A Strohman, W Legon - Brain Stimulation, 2024 - Elsevier
Background Low-intensity focused ultrasound (LIFU) is a promising form of non-invasive
neuromodulation characterized by a rich parameter space that includes intensity, duration …

A multi-frequency sparse hemispherical ultrasound phased array for microbubble-mediated transcranial therapy and simultaneous cavitation map**

L Deng, MA O'Reilly, RM Jones, R An… - Physics in Medicine & …, 2016 - iopscience.iop.org
Focused ultrasound (FUS) phased arrays show promise for non-invasive brain therapy.
However, the majority of them are limited to a single transmit/receive frequency and …

Full-matrix phase shift migration method for transcranial ultrasonic imaging

C Jiang, Y Li, K Xu, D Ta - IEEE transactions on ultrasonics …, 2020 - ieeexplore.ieee.org
A spectrum-domain method, called full-matrix phase shift migration (FM-PSM), is presented
for transcranial ultrasound phase correction and imaging with ideal synthetic aperture …

Ultrashort echo‐time MRI versus CT for skull aberration correction in MR‐guided transcranial focused ultrasound: In vitro comparison on human calvaria

GW Miller, M Eames, J Snell, JF Aubry - Medical physics, 2015 - Wiley Online Library
Purpose: Transcranial magnetic resonance‐guided focused ultrasound (TcMRgFUS) brain
treatment systems compensate for skull‐induced beam aberrations by adjusting the phase …

MRI compatible head phantom for ultrasound surgery

G Menikou, T Dadakova, M Pavlina, M Bock… - Ultrasonics, 2015 - Elsevier
Objective Develop a magnetic resonance imaging (MRI) compatible head phantom with
acoustic attenuation closely matched to the human attenuation, and suitable for testing …